Histopathological evaluation of wound healing by extracts from Glaucium corniculatum (L. ) Curt.

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Arefyar r.; MIROLIAEI M.; TALEBI A.; ZAHMATKESH M.

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Journal: Journal of Molecular and Cellular Researches Year:2018 | Volume:31 | Issue:1 Page(s): 1-15

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Title

Histopathological evaluation of wound healing by extracts from Glaucium corniculatum (L. ) Curt.

Author(s)

Arefyar r. | MIROLIAEI M. | TALEBI A. | ZAHMATKESH M. | Issue Writer Certificate

Keywords

wound healingQ2

dermisQ2

epidermisQ1

plant extractQ1

MamisaQ1

Abstract

Reducing the complications of wounds and speeding up the wound healing process are among the topics of research in the field of surgery science. There is genral interest in identifying efficient and cost-effective medicines, particularly herbal products. This study was aimed to investigate the effect of hydro-alcoholic extracts of Mamisa plant (Khashkhash Bahri) on wound healing and to compare the effects with that of tetracycline in adult male rats. 30 male albino rats were randomly divided into three groups of 10 rats. After wounding the rats in a similar condition, the effects of Mamisa plant and tetracycline ointment on healing noninfectious wounds were examined. Accordingly, a control group was also considered. After seven and fourteen days of treatment the trend of wound healing process was examined in the dermis and epidermis layers of all groups. Compared with the control, the herbal treated group showed a significant healing (p < 0. 05). Based on the obtained results, it seems that the hydro alcoholic extract from Mamisa plant, its alkaloid and flavonoids compounds speed up the wound healing in the dermis and epidermis layers.

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APA: Copy

Arefyar, r., MIROLIAEI, M., TALEBI, A., & ZAHMATKESH, M.. (2018). Histopathological evaluation of wound healing by extracts from Glaucium corniculatum (L. ) Curt.. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 31(1 ), 1-15. SID. https://sid.ir/paper/248428/en

Vancouver: Copy

Arefyar r., MIROLIAEI M., TALEBI A., ZAHMATKESH M.. Histopathological evaluation of wound healing by extracts from Glaucium corniculatum (L. ) Curt.. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2018;31(1 ):1-15. Available from: https://sid.ir/paper/248428/en

IEEE: Copy

r. Arefyar, M. MIROLIAEI, A. TALEBI, and M. ZAHMATKESH, “Histopathological evaluation of wound healing by extracts from Glaucium corniculatum (L. ) Curt.,” JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 31, no. 1 , pp. 1–15, 2018, [Online]. Available: https://sid.ir/paper/248428/en

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