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Information Journal Paper

Title

HISTOPATHOLOGICAL EVALUATION OF NON-INFECTIOUS SKIN DEEP WOUND HEALING ACTIVITY OF HERBAL EXTRACT

Pages

  212-222

Abstract

 Despite major advances in treatment of wound, healing remained as one of the most important challenges ahead. Since antioxidant, antimicrobial and anti-inflammatory properties of MELISSA OFFICINALIS, ZIZYPHUS SPINA-CHRISTI, ALTHAEA OFFICINALIS, Satureja bachtiarica have been proven and these properties are involved in WOUND HEALING, The present investigation was undertaken to assess the efficacy of mentioned officinal herbs hydroalcoholic extracts on thickness and non-septic WOUND HEALING model in rat. Each extract was co-administered for 7 and 14 consecutive days on 50 experimental wounded rats. Macroscopic observations showed all applied hydroalcoholic extracts had WOUND HEALING potentials.Althaea officinalis extract presented the most activity in WOUND HEALING specified by significant increase in wound contraction. Furthermore, histopathological assessments confirmed the WOUND HEALING potential of Althaea extract.This could be attributed to the induction effects of a typical fibroblast affecting wound contraction. It was observed a combined hydroalcoholic extract from all herbs also possesses WOUND HEALING potential properties less than ALTHAEA OFFICINALIS.

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    APA: Copy

    MIROLIAEI, M., CHELONGAR, R., AMINJAFARI, A., TALEBI, A., & GHIYAS, M.. (2017). HISTOPATHOLOGICAL EVALUATION OF NON-INFECTIOUS SKIN DEEP WOUND HEALING ACTIVITY OF HERBAL EXTRACT. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 30(2 ), 212-222. SID. https://sid.ir/paper/248599/en

    Vancouver: Copy

    MIROLIAEI M., CHELONGAR R., AMINJAFARI A., TALEBI A., GHIYAS M.. HISTOPATHOLOGICAL EVALUATION OF NON-INFECTIOUS SKIN DEEP WOUND HEALING ACTIVITY OF HERBAL EXTRACT. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2017;30(2 ):212-222. Available from: https://sid.ir/paper/248599/en

    IEEE: Copy

    M. MIROLIAEI, R. CHELONGAR, A. AMINJAFARI, A. TALEBI, and M. GHIYAS, “HISTOPATHOLOGICAL EVALUATION OF NON-INFECTIOUS SKIN DEEP WOUND HEALING ACTIVITY OF HERBAL EXTRACT,” JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 30, no. 2 , pp. 212–222, 2017, [Online]. Available: https://sid.ir/paper/248599/en

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