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Information Journal Paper

Title

The effect of Estradiol and growth hormone on mean plasma Ghrelin concentration in adult sheeps with food restriction

Pages

  18-25

Abstract

Ghrelin is an Orexigenic hormone that mainly secreted from human gastric cells. Estraidol has a negative effect on the secretion of these hormone. The goal of the present study was to investigate the effect of Estradiol and simultaneous injection of Estradiol and Growth hormone on mean Ghrelin concentration in Sheeps that are fed with either restricted or non restricted diets. In this study 10 Sheep were randomly divided in two groups (n=5) and were fed either by restricted or non restricted diets for a week. Animals in both groups received Estradiol (2mg/kg) and simultaneous injection of Estradiol (2 mg/kg) and GH (0. 1 mg/kg), on 7th and 8th day of the experiment respectively. Ghrelin concentration was determined by RIA. In the restricted group, Ghrelin concentrations increased significantly on the 7th of the experiment, compared to the 1st day (p≤ 0. 05). While in the non restricted group, no significant change was observed. Estradiol significantly decreased Ghrelin levels after injection compared to before injection in both groups (p≤ 0. 05). In both groups, simultaneous injection of Estradiol and GH increased Ghrelin concentration significantly. Food restriction lead to increases in levels of Ghrelin. Estradiol has a negative effect on Ghrelin secretion. Growth hormone exert a stimulatory effect on Ghrelin secretion and this effect is stronger than the reducing effect of Estradiol on Ghrelin concentration. However, the effect of 17-b-Estradiol with Growth hormone on mean plasma concentration of Ghrelin in Sheep has never been examined therefore.

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    APA: Copy

    Behdadvand, g., KHAZALI, H., & ROKNI, H.. (2016). The effect of Estradiol and growth hormone on mean plasma Ghrelin concentration in adult sheeps with food restriction. JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 29(1 ), 18-25. SID. https://sid.ir/paper/248730/en

    Vancouver: Copy

    Behdadvand g., KHAZALI H., ROKNI H.. The effect of Estradiol and growth hormone on mean plasma Ghrelin concentration in adult sheeps with food restriction. JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2016;29(1 ):18-25. Available from: https://sid.ir/paper/248730/en

    IEEE: Copy

    g. Behdadvand, H. KHAZALI, and H. ROKNI, “The effect of Estradiol and growth hormone on mean plasma Ghrelin concentration in adult sheeps with food restriction,” JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 29, no. 1 , pp. 18–25, 2016, [Online]. Available: https://sid.ir/paper/248730/en

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