ASSESSMENT OF VOCATION OF RIFABUTIN AND RIFAPENTINE IN REPLACE OF RIFAMPCIN IN DRUG RESISTANCE LEPROSY PATIENTS: A MOLECULAR SIMULATION STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOHANTY PARTHA SARATHI; NAAZ FARAH; BANSAL AVI KUMAR; GUPTA UMESH DATTA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS Year:2017 | Volume:6 | Issue:3 Page(s): 113-122

Download Full-Text

View:

254

Download:

Cites:

Information Journal Paper

Title

ASSESSMENT OF VOCATION OF RIFABUTIN AND RIFAPENTINE IN REPLACE OF RIFAMPCIN IN DRUG RESISTANCE LEPROSY PATIENTS: A MOLECULAR SIMULATION STUDY

Author(s)

MOHANTY PARTHA SARATHI | NAAZ FARAH | BANSAL AVI KUMAR | GUPTA UMESH DATTA | Issue Writer Certificate

Keywords

RIFAMPICIN

RIFABUTIN

RIFAPENTINE

LEPROSY

DRUG RESISTANCE

DOCKING

Abstract

The emergence of DRUG RESISTANCE in LEPROSY is a major hurdle in LEPROSY elimination programme. Although the problem of DRUG RESISTANCE is presently not acute, it is important that we collect data more systematically and monitor the trend carefully so that effective measures to combat this problem can be developed. The present study aimed at the explication of cross resistance of RIFABUTIN and RIFAPENTINE to RIFAMPICIN which would be helpful to programme managers for implementing RIFABUTIN or RIFAPENTINE in replace of RIFAMPICIN. In this study we built 3D model of the M. leprae rpoB using Swiss Model and the modelled structure was docked with RIFAMPICIN, RIFABUTIN and RIFAPENTINE. We established that these 3 antibiotics interact with the same binding region in the modelled rpoB of M. leprae. Thus we conclude that vocation of RIFABUTIN and RIFAPENTINE could not be suitable in replace of RIFAMPICIN to combat with DRUG RESISTANCE LEPROSY.

Cites

No record.

References

No record.

Cite

APA: Copy

MOHANTY, PARTHA SARATHI, NAAZ, FARAH, BANSAL, AVI KUMAR, & GUPTA, UMESH DATTA. (2017). ASSESSMENT OF VOCATION OF RIFABUTIN AND RIFAPENTINE IN REPLACE OF RIFAMPCIN IN DRUG RESISTANCE LEPROSY PATIENTS: A MOLECULAR SIMULATION STUDY. MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS, 6(3), 113-122. SID. https://sid.ir/paper/336238/en

Vancouver: Copy

MOHANTY PARTHA SARATHI, NAAZ FARAH, BANSAL AVI KUMAR, GUPTA UMESH DATTA. ASSESSMENT OF VOCATION OF RIFABUTIN AND RIFAPENTINE IN REPLACE OF RIFAMPCIN IN DRUG RESISTANCE LEPROSY PATIENTS: A MOLECULAR SIMULATION STUDY. MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS[Internet]. 2017;6(3):113-122. Available from: https://sid.ir/paper/336238/en

IEEE: Copy

PARTHA SARATHI MOHANTY, FARAH NAAZ, AVI KUMAR BANSAL, and UMESH DATTA GUPTA, “ASSESSMENT OF VOCATION OF RIFABUTIN AND RIFAPENTINE IN REPLACE OF RIFAMPCIN IN DRUG RESISTANCE LEPROSY PATIENTS: A MOLECULAR SIMULATION STUDY,” MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS, vol. 6, no. 3, pp. 113–122, 2017, [Online]. Available: https://sid.ir/paper/336238/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops