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Information Journal Paper

Title

COMPARISON OF PAP SMEAR AND COLPOSCOPY IN SCREENING FOR CERVICAL CANCER IN PATIENTS WITH SECONDARY IMMUNODEFICIENCY

Pages

  1542-1548

Abstract

 Introduction: CERVICAL CANCER is the second most common cancer among women worldwide. The SENSITIVITY of CONVENTIONAL PAP SMEAR in detecting cervical lesions before CERVICAL CANCER is 51%, which means the false negative value is 49%. The aim of this study was to compare two methods for screening for CERVICAL CANCER in patients with secondary IMMUNODEFICIENCY, i.e., the CONVENTIONAL PAP SMEAR and COLPOSCOPY.Methods: This cross-sectional study was conducted on 101 immunodeficient patients who were referred to the Gynecologic Clinic at Shahid Sadughi Hospital in Yazd from March 2011 to August 2012. All patients underwent the Pap test, a COLPOSCOPY, and a cervical biopsy, with the latter being considered as the gold-standard test.Results: The most frequency of IMMUNODEFICIENCY was noted among patients with rheumatoid arthritis (53.3%), and this was followed by patients who were undergoing chemotherapy (30.7%), patients with lupus erythematosus (12.9%), and patients with AIDS (3%). The SENSITIVITY, SPECIFICITY, positive predictive value, negative predictive value, and accuracy of the Pap smear were18.2, 98.5, 85.5, 71.3, and 72.2%, respectively. The respective values for COLPOSCOPY were 66.7, 98.94, 80, 97.9, and 97%, respectively.Conclusion: In this study the accuracy, SENSITIVITY, SPECIFICITY, and negative predictive values of COLPOSCOPY were higher than those for the Pap smear in detecting high-grade, cervical, pre-malignant lesions (cervical intraepithelial neoplasia: CIN≥ 2). Therefore, an annual COLPOSCOPY is advised for secondary immunodeficient patients instead of a Pap smear.

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    APA: Copy

    KARIMI ZARCHI, MOJGAN, ZANBAGH, LEILA, SHAFII, ALIREZA, TAGHIPOUR ZAHIR, SHOKOUH, TEIMOORI, SORAYA, & YAZDIAN ANARI, POURIA. (2015). COMPARISON OF PAP SMEAR AND COLPOSCOPY IN SCREENING FOR CERVICAL CANCER IN PATIENTS WITH SECONDARY IMMUNODEFICIENCY. ELECTRONIC PHYSICIAN, 7(7), 1542-1548. SID. https://sid.ir/paper/345391/en

    Vancouver: Copy

    KARIMI ZARCHI MOJGAN, ZANBAGH LEILA, SHAFII ALIREZA, TAGHIPOUR ZAHIR SHOKOUH, TEIMOORI SORAYA, YAZDIAN ANARI POURIA. COMPARISON OF PAP SMEAR AND COLPOSCOPY IN SCREENING FOR CERVICAL CANCER IN PATIENTS WITH SECONDARY IMMUNODEFICIENCY. ELECTRONIC PHYSICIAN[Internet]. 2015;7(7):1542-1548. Available from: https://sid.ir/paper/345391/en

    IEEE: Copy

    MOJGAN KARIMI ZARCHI, LEILA ZANBAGH, ALIREZA SHAFII, SHOKOUH TAGHIPOUR ZAHIR, SORAYA TEIMOORI, and POURIA YAZDIAN ANARI, “COMPARISON OF PAP SMEAR AND COLPOSCOPY IN SCREENING FOR CERVICAL CANCER IN PATIENTS WITH SECONDARY IMMUNODEFICIENCY,” ELECTRONIC PHYSICIAN, vol. 7, no. 7, pp. 1542–1548, 2015, [Online]. Available: https://sid.ir/paper/345391/en

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