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Information Journal Paper

Title

The protective effects of quercetin against malathion-induced oxidative stress and myocardial damage in in Wistar male rats

Pages

  63-71

Abstract

 Aim: In this study the protective effects of Quercetin were investigated on myocardial tissue damage in male Wistar rats during Malathion poisoning. Material and Methods: The study was performed on seven groups; each group contained six male rats. After 24 h of intraperitoneal injection of Quercetin, Malathion or a combination of them, the heart of the animals was separated, and its tissue slice was prepared. After tissue homogenization, the parameters of Oxidative stress were measured. Results: Intraperitoneal injection of 200 mg/kg of Malathion significantly induced the lipid peroxidation (p<0. 01) and Oxidative stress (p<0. 001), necrosis and inflammation in myocardial tissue. However, intraperitoneal injection of 50mg/kg Quercetin reduced Malathion-induced toxicity on lipid peroxidation (p<0. 001), Oxidative stress (p<0. 05), inflammation and myocardial tissue damage. Conclusion: The results suggested that Quercetin is able to improve myocardial tissue damage and restore the rate of Oxidative stress in Malathion-treated groups in the normal level.

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    APA: Copy

    YOUSEFI, R., HATAMI NEMATI, H., SHAHBAZI, F., ALI HEMMATI, A.R., & AHMADI, H.. (2019). The protective effects of quercetin against malathion-induced oxidative stress and myocardial damage in in Wistar male rats. JOURNAL OF CELL & TISSUE, 10(2 ), 63-71. SID. https://sid.ir/paper/361252/en

    Vancouver: Copy

    YOUSEFI R., HATAMI NEMATI H., SHAHBAZI F., ALI HEMMATI A.R., AHMADI H.. The protective effects of quercetin against malathion-induced oxidative stress and myocardial damage in in Wistar male rats. JOURNAL OF CELL & TISSUE[Internet]. 2019;10(2 ):63-71. Available from: https://sid.ir/paper/361252/en

    IEEE: Copy

    R. YOUSEFI, H. HATAMI NEMATI, F. SHAHBAZI, A.R. ALI HEMMATI, and H. AHMADI, “The protective effects of quercetin against malathion-induced oxidative stress and myocardial damage in in Wistar male rats,” JOURNAL OF CELL & TISSUE, vol. 10, no. 2 , pp. 63–71, 2019, [Online]. Available: https://sid.ir/paper/361252/en

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