Phenotypic study of Extended-spectrum Beta lactamase (ESBL) producing isolates of Acinetobacter baumannii in patients reffered to a military hospital in Guilan province

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Saleh Nia Samak A.; NOJOOMI F.

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Journal: Journal of Molecular and Cellular Researches Year:2019 | Volume:32 | Issue:4 Page(s): 578-590

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Title

Phenotypic study of Extended-spectrum Beta lactamase (ESBL) producing isolates of Acinetobacter baumannii in patients reffered to a military hospital in Guilan province

Author(s)

Saleh Nia Samak A. | NOJOOMI F. | Issue Writer Certificate

Keywords

Acinetobacter baumanniiQ1

Extended-spectrum Beta lactamaseQ1

Drug resistanceQ1

Hospitalized infectionQ2

Abstract

Acinetobacter is a kind of non-fermentative gram-negative cocobacilli which is considered as the second major cause of Hospitalized infections after Pseudomonas aeruginosa. The Beta lactamase enzymes of these bacteria are very diverse and their constantly point mutations have led to the emergence of Extended-spectrum Beta lactamases ( ESBLs). In this study, which took place in a period of eight months, after confirmation of the identity of Acinetobacter strains by bacteriological tests, the pattern of Drug resistance of the isolates and the production of ESBLs by them was investigated by Agar disk diffusion method. In this study, 50 strains of Acinetobacter baumannii and 15 strains of other Acinetobacter species were isolated from patients. The highest frequency of Drug resistance in Acinetobacter baumannii isolates was related to Cefipime (100%), and the lowest was related to Cefixime-Clavulanic acid (50%). Acinetobacter with Multiple Resistance Patterns are a growing problem for medical centers around the world and the most important reason for this is the unnecessary and over-consumption of drugs, especially Beta lactam antibiotics.

Cites

Evaluation of the Antimicrobial Ability of Probiotics Against Nosocomial Infections by Inhibiting Ompa Gene Expression in Acinetobacter Baumannii

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APA: Copy

Saleh Nia Samak, A., & NOJOOMI, F.. (2019). Phenotypic study of Extended-spectrum Beta lactamase (ESBL) producing isolates of Acinetobacter baumannii in patients reffered to a military hospital in Guilan province. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 32(4 ), 578-590. SID. https://sid.ir/paper/369698/en

Vancouver: Copy

Saleh Nia Samak A., NOJOOMI F.. Phenotypic study of Extended-spectrum Beta lactamase (ESBL) producing isolates of Acinetobacter baumannii in patients reffered to a military hospital in Guilan province. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2019;32(4 ):578-590. Available from: https://sid.ir/paper/369698/en

IEEE: Copy

A. Saleh Nia Samak, and F. NOJOOMI, “Phenotypic study of Extended-spectrum Beta lactamase (ESBL) producing isolates of Acinetobacter baumannii in patients reffered to a military hospital in Guilan province,” JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 32, no. 4 , pp. 578–590, 2019, [Online]. Available: https://sid.ir/paper/369698/en

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