Ursolic Acid: 5 cyclic triterpenoid in apple peel with a wide range of therapeutic effects

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AHMADZADEH S.; BAKHTIARI N.

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Journal: Journal of Molecular and Cellular Researches Year:2019 | Volume:32 | Issue:2 Page(s): 258-268

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Information Journal Paper

Title

Ursolic Acid: 5 cyclic triterpenoid in apple peel with a wide range of therapeutic effects

Author(s)

AHMADZADEH S. | BAKHTIARI N. | Issue Writer Certificate

Keywords

Ursolic AcidQ1

5 cyclic triterpenoidQ1

anti-cancerQ1

anti-diabeticQ1

antiinflammatoryQ1

Abstract

Ursolic Acid ( as known, ursol, prunol, malol, 3β-hydroxyl-urs-12-en-28-oic acid) is a natural lipophilic, triterpenoid which exist in wide range of plant and fruits. In recent decades, it was appreciated due to biological potential and therapeutic effects of this compound. In this review article, it is tried to explain the source of food which exist Ursolic Acid, biosynthesis, extraction and purification, absorption level, distribution, and also pratective effects on the body organs such as brain, skeletal muscle, liver and pharmacological effects such as anti-cancer effect, anti-inflammatory, anti-diabetics and anti-microbila in opposed of variety of bacteria, fungi and virus as like as HIV, HBV. In addition, this review study showed that Ursolic Acid may a potential candidate in prevention of dysfunction and diseases such as Alzheimer, atherosclerosis, muscle atrophy, pulmonary inflammation, overweight, the type of cancers (liver, stomach, intestine, pancreas, skin and so on), diabetes type 2, HIV and also aging and age-related diseases. Finally, this article hoped to present beneficial effects of Ursolic Acid in utilizing of food, drug, medicine, cosmetics.

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APA: Copy

AHMADZADEH, S., & BAKHTIARI, N.. (2019). Ursolic Acid: 5 cyclic triterpenoid in apple peel with a wide range of therapeutic effects. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 32(2 ), 258-268. SID. https://sid.ir/paper/373805/en

Vancouver: Copy

AHMADZADEH S., BAKHTIARI N.. Ursolic Acid: 5 cyclic triterpenoid in apple peel with a wide range of therapeutic effects. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2019;32(2 ):258-268. Available from: https://sid.ir/paper/373805/en

IEEE: Copy

S. AHMADZADEH, and N. BAKHTIARI, “Ursolic Acid: 5 cyclic triterpenoid in apple peel with a wide range of therapeutic effects,” JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 32, no. 2 , pp. 258–268, 2019, [Online]. Available: https://sid.ir/paper/373805/en

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