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Information Journal Paper

Title

A Comparison of the Effect of 12 Weeks of Interval Training with High and Moderate Intensity on Perilipin 3 of Visceral Adipose Tissue and Insulin Resistance in Type 2 Diabetic Male Rats

Pages

  35-48

Abstract

 The aim of this study was to compare the effect of 12 weeks of interval training with high and moderate intensity on perilipin 3 (PLIN3) of visceral adipose tissue and insulin resistance in type 2 diabetic male rats. In this study, 24 male rats with type 2 diabetes were randomly divided into three groups: interval training with moderate intensity (MIIT), interval training with high intensity (HIIT) and control. Interval training (HIIT, MIIT) was applied for 12 weeks, 5 sessions per week. The MIIT protocol included 13 four-min. bouts of activity with intensity of 65-70% vo2max and the HIIT protocol included 10 four-min. bouts of activity with intensity of 85-90% vo2max with 2-minute active rest periods. Western Blot method was used to measure PLIN3 protein levels. ANOVA and Tukey's test were used for data analysis. The results indicated a significant decrease in PLIN3 in the HIIT and MIIT groups compared with the control group (P=0. 001). However, there was no significant difference between the training groups (P=0. 274). Also, both HIIT and MIIT protocols significantly decreased serum levels of glucose (P=0. 001), while they had no significant effects on serum insulin and insulin resistance (P˃ 0. 05). There was no significant difference between training groups in insulin, glucose and insulin resistance changes (P˃ 0. 05). The findings of this study showed that both HIIT and MIIT protocols drastically reduced PLIN3 of visceral adipose and improved glucose metabolism in type 2 diabetic rats. Therefore, it seems that PLIN3 changes in visceral adipose are independent of the training intensity.

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    APA: Copy

    Moghaddami, Kamilia, MOHEBBI, HAMID, Tabari, Elma, & Faridnia, Mehrsa. (2019). A Comparison of the Effect of 12 Weeks of Interval Training with High and Moderate Intensity on Perilipin 3 of Visceral Adipose Tissue and Insulin Resistance in Type 2 Diabetic Male Rats. SPORT BIOSCIENCES (HARAKAT), 11(1 ), 35-48. SID. https://sid.ir/paper/375478/en

    Vancouver: Copy

    Moghaddami Kamilia, MOHEBBI HAMID, Tabari Elma, Faridnia Mehrsa. A Comparison of the Effect of 12 Weeks of Interval Training with High and Moderate Intensity on Perilipin 3 of Visceral Adipose Tissue and Insulin Resistance in Type 2 Diabetic Male Rats. SPORT BIOSCIENCES (HARAKAT)[Internet]. 2019;11(1 ):35-48. Available from: https://sid.ir/paper/375478/en

    IEEE: Copy

    Kamilia Moghaddami, HAMID MOHEBBI, Elma Tabari, and Mehrsa Faridnia, “A Comparison of the Effect of 12 Weeks of Interval Training with High and Moderate Intensity on Perilipin 3 of Visceral Adipose Tissue and Insulin Resistance in Type 2 Diabetic Male Rats,” SPORT BIOSCIENCES (HARAKAT), vol. 11, no. 1 , pp. 35–48, 2019, [Online]. Available: https://sid.ir/paper/375478/en

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