Effect of fenugreek (Trigonella foenum graecum L. ) ethanolic extract on carbon tetrachloride-induced hepatotoxicity in rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Shirinabadi farahani F.; EIDI A.; MORTAZAVI P.; HAERI ROHANI A.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ) Year:2020 | Volume:14 | Issue:1 (53) Page(s): 1-12

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

244

Download:

Cites:

Information Journal Paper

Title

Effect of fenugreek (Trigonella foenum graecum L. ) ethanolic extract on carbon tetrachloride-induced hepatotoxicity in rats

Author(s)

Shirinabadi farahani F. | EIDI A. | MORTAZAVI P. | HAERI ROHANI A. | Issue Writer Certificate

Keywords

Carbon tetrachlorideQ1

LiverQ2

DetoxificationQ1

Fenugreek (Trigonella foenum graecum)Q1

RatQ2

Abstract

Fenugreek (Trigonella foenum graecum) has long been considered in traditional medicine due to its botanical and medicinal properties. The aim of this study was to evaluate the protective effect of fenugreek seed extract against Carbon tetrachloride (CCl4)-induced hepatic toxicity in Rats. A total of 48 male Wistar Rats were randomly divided into eight groups. The normal control group was intact. The Liver-injury control group received intraperitoneal injection of 50% CCl4 (1 ml/kg) twice a week for a total of 10 times. Normal experimental groups received fenugreek extract (50, 100 and 200 mg/kg intragastrically). Liver-injury experimental groups were administRated fenugreek extract (3 doses as above) along with CCl4. The Rats were sacrificed on the 34 th day, blood was withdrawn by cardiac puncture and the levels of ALT, AST, ALP, and GGT were measured. AdministRation of CCl4 significantly increased the levels of Liver enzymes in the Liver-injury control group in comparison to normal control (p<0. 001). AdministRation of fenugreek extract showed a significant tendency towards normalization of all measured biochemical parameters in CCl4-treated Rats. These results demonstRate that fenugreek extract exerts protective effects against CCl4-induced damage in Rat Liver, and supports a potential therapeutic use of fenugreek as an alternative for patients with Liver diseases.

Cites

No record.

References

No record.

Cite

APA: Copy

Shirinabadi farahani, F., EIDI, A., MORTAZAVI, P., & HAERI ROHANI, A.. (2020). Effect of fenugreek (Trigonella foenum graecum L. ) ethanolic extract on carbon tetrachloride-induced hepatotoxicity in rats. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 14(1 (53) ), 1-12. SID. https://sid.ir/paper/398630/en

Vancouver: Copy

Shirinabadi farahani F., EIDI A., MORTAZAVI P., HAERI ROHANI A.. Effect of fenugreek (Trigonella foenum graecum L. ) ethanolic extract on carbon tetrachloride-induced hepatotoxicity in rats. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2020;14(1 (53) ):1-12. Available from: https://sid.ir/paper/398630/en

IEEE: Copy

F. Shirinabadi farahani, A. EIDI, P. MORTAZAVI, and A. HAERI ROHANI, “Effect of fenugreek (Trigonella foenum graecum L. ) ethanolic extract on carbon tetrachloride-induced hepatotoxicity in rats,” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 14, no. 1 (53) , pp. 1–12, 2020, [Online]. Available: https://sid.ir/paper/398630/en

Related Journal Papers