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Information Journal Paper

Title

Laboratory production of hyperimmune serum against Bovine ephemeral fever virus isolated in Iran

Pages

  166-175

Abstract

 Considering the numerous applications of polyclonal antibodies in research and clinical fields, the development of methods for preparation of hyperimmune serum against pathogens is very important. In this research, a method for producing hyperimmune serum against bovine ephemeral fever virus was introduced. The hyperimmune serum was raised in rabbit using at least 10 6. 7 TCID50 of the whole viral particle which was administered intravenously without adjuvant. Antigen presentation was carried out at 0, 1 and 4 weeks intervals. In comparison to the previous studies, this schedule resulted in a high titer of hyperimmune serum against the virus as the mean of neutralizing antibodies was determined at 1625. The hyperimmune serum as a biological product of this research will definitely be exploited in the experiments required for research as well as possible commercial applications in the future. This method is also introduced for producing hyperimmune serum against other viruses, especially Rhabdoviruses.

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    APA: Copy

    ALMASI, S., & BAKHSHESH, M.. (2019). Laboratory production of hyperimmune serum against Bovine ephemeral fever virus isolated in Iran. JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 32(2 ), 166-175. SID. https://sid.ir/paper/406623/en

    Vancouver: Copy

    ALMASI S., BAKHSHESH M.. Laboratory production of hyperimmune serum against Bovine ephemeral fever virus isolated in Iran. JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2019;32(2 ):166-175. Available from: https://sid.ir/paper/406623/en

    IEEE: Copy

    S. ALMASI, and M. BAKHSHESH, “Laboratory production of hyperimmune serum against Bovine ephemeral fever virus isolated in Iran,” JOURNAL OF ANIMAL RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 32, no. 2 , pp. 166–175, 2019, [Online]. Available: https://sid.ir/paper/406623/en

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