ISOLATION AND IDENTIFICATION OF IOVASTATIN –PRODUCING MICROORGANISM AND DETERMINATION OF OPTIMAL FERMENTATION CONDITIONS

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ANVARI MASOUMEH; KHAYATI GHOLAM

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Journal: JOURNAL OF SCIENCE (KHARAZMI UNIVERSITY) Year:2005 | Volume:5 | Issue:1-2 Page(s): 497-504

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Title

ISOLATION AND IDENTIFICATION OF IOVASTATIN –PRODUCING MICROORGANISM AND DETERMINATION OF OPTIMAL FERMENTATION CONDITIONS

Author(s)

ANVARI MASOUMEH | KHAYATI GHOLAM | Issue Writer Certificate

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Abstract

From 28 Aspergillus terreus, three produced lovastatin with equivalent or better yield than strain ATCC 20542 originally described for lovastatin production. Medium optimization experiments with the best isolate (Gil- 4) indicated that lactose, soya meal and KN03 were the best sources carbon, organic nitrogen and inorganic nitrogen sources, respectively. In shake-flasks with optimized medium containing 4 % (w/v) lactose, 400 g lovastatinlml was produced, with a yield of 10 mg/g lactose. In solid substrate fermentation on extracted sweet sorghum pulp supplemented with cheese whey 1500 g lovastating dry weight was produced with yield of 37.5 mg/g lactose.

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APA: Copy

ANVARI, MASOUMEH, & KHAYATI, GHOLAM. (2005). ISOLATION AND IDENTIFICATION OF IOVASTATIN –PRODUCING MICROORGANISM AND DETERMINATION OF OPTIMAL FERMENTATION CONDITIONS. JOURNAL OF SCIENCE (KHARAZMI UNIVERSITY), 5(1-2), 497-504. SID. https://sid.ir/paper/43905/en

Vancouver: Copy

ANVARI MASOUMEH, KHAYATI GHOLAM. ISOLATION AND IDENTIFICATION OF IOVASTATIN –PRODUCING MICROORGANISM AND DETERMINATION OF OPTIMAL FERMENTATION CONDITIONS. JOURNAL OF SCIENCE (KHARAZMI UNIVERSITY)[Internet]. 2005;5(1-2):497-504. Available from: https://sid.ir/paper/43905/en

IEEE: Copy

MASOUMEH ANVARI, and GHOLAM KHAYATI, “ISOLATION AND IDENTIFICATION OF IOVASTATIN –PRODUCING MICROORGANISM AND DETERMINATION OF OPTIMAL FERMENTATION CONDITIONS,” JOURNAL OF SCIENCE (KHARAZMI UNIVERSITY), vol. 5, no. 1-2, pp. 497–504, 2005, [Online]. Available: https://sid.ir/paper/43905/en

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