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Information Journal Paper

Title

CLASS-PI OF GLUTATHIONE S-TRANSFERASES

Pages

  1-16

Abstract

 Class-Pi of glutathione s-transferases (GST-Pi) is the specific form of GSTs that are known to participate particularly in the mechanisms of resistance to drugs and carcinogens. This class of the enzyme is referred to as class-P or class-Pi or class π. The accepted terminology in this review article is class-Pi. In this article following a brief description of identified molecular forms of GSTs, we focus on GST-Pi. We review new findings about the structure and regulation of GST-Pi gene. Then, the role of GST-Pi in liver damage, OXIDATIVE STRESS, CARCINOGENESIS and DRUG RESISTANCE are discussed. Also, the presence of common genetic POLYMORPHISM, hypermethylation in GST-Pi gene and the consequences GST-Pi knock out is regarded.

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    Cite

    APA: Copy

    KAZEMNEZHAD, S., RASMI, Y., SHARIFI, R., & ALAMEH, A.A.. (2006). CLASS-PI OF GLUTATHIONE S-TRANSFERASES. IRANIAN JOURNAL OF BIOTECHNOLOGY, 4(1), 1-16. SID. https://sid.ir/paper/532895/en

    Vancouver: Copy

    KAZEMNEZHAD S., RASMI Y., SHARIFI R., ALAMEH A.A.. CLASS-PI OF GLUTATHIONE S-TRANSFERASES. IRANIAN JOURNAL OF BIOTECHNOLOGY[Internet]. 2006;4(1):1-16. Available from: https://sid.ir/paper/532895/en

    IEEE: Copy

    S. KAZEMNEZHAD, Y. RASMI, R. SHARIFI, and A.A. ALAMEH, “CLASS-PI OF GLUTATHIONE S-TRANSFERASES,” IRANIAN JOURNAL OF BIOTECHNOLOGY, vol. 4, no. 1, pp. 1–16, 2006, [Online]. Available: https://sid.ir/paper/532895/en

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