OPTIMIZATION OF A FED-BATCH FERMENTER PRODUCING BAKER’S YEAST USING SIMULATED ANNEALING METHOD

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GHAHRAMANI HOSSEIN; PISHVAEI M.R.; VOSOUGHI MANOUCHEHR; SEYF KORDI A.A.

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Journal: IRANIAN JOURNAL OF BIOTECHNOLOGY Year:2009 | Volume:7 | Issue:3 Page(s): 157-165

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Title

OPTIMIZATION OF A FED-BATCH FERMENTER PRODUCING BAKER’S YEAST USING SIMULATED ANNEALING METHOD

Author(s)

GHAHRAMANI HOSSEIN | PISHVAEI M.R. | VOSOUGHI MANOUCHEHR | SEYF KORDI A.A. | Issue Writer Certificate

Keywords

SIMULATED ANNEALING

OPTIMIZATION

FERMENTATION

FED-BATCH

S. CEREVISIAE

Abstract

Modeling of fermentation processes is so complicated and uncertain; therefore it is necessary to provide a robust and appropriate dynamic optimization method. In order to obtain the maximum amount of yeast (Saccharomyces cerevisiae), the bioreactor must be operated under optimal conditions. To determine substrate feeding in a fed-batch bioreactor, a simulated annealing (SA) approach was examined. The optimal glucose feed rate profiles were computed by a stochastic and deterministic problems for various initial conditions to investigate their effects on optimal operation of the fed-batch bioreactor. Results declared a proper capability of SA method for determination of optimal feeding policies in fermentation processes. The major advantage of the simulated annealing is its capability for handling the problems with model mismatches. Finally, an open loop sensitivity analysis of SA optimization method was tested by a mathematical model to note the effect of some key variables in the subsequent optimization study on the fermenter. Findings show slight difference between trends, thus the SA algorithm is an efficient, robust and satisfactory acceptable.

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APA: Copy

GHAHRAMANI, HOSSEIN, PISHVAEI, M.R., VOSOUGHI, MANOUCHEHR, & SEYF KORDI, A.A.. (2009). OPTIMIZATION OF A FED-BATCH FERMENTER PRODUCING BAKER’S YEAST USING SIMULATED ANNEALING METHOD. IRANIAN JOURNAL OF BIOTECHNOLOGY, 7(3), 157-165. SID. https://sid.ir/paper/557039/en

Vancouver: Copy

GHAHRAMANI HOSSEIN, PISHVAEI M.R., VOSOUGHI MANOUCHEHR, SEYF KORDI A.A.. OPTIMIZATION OF A FED-BATCH FERMENTER PRODUCING BAKER’S YEAST USING SIMULATED ANNEALING METHOD. IRANIAN JOURNAL OF BIOTECHNOLOGY[Internet]. 2009;7(3):157-165. Available from: https://sid.ir/paper/557039/en

IEEE: Copy

HOSSEIN GHAHRAMANI, M.R. PISHVAEI, MANOUCHEHR VOSOUGHI, and A.A. SEYF KORDI, “OPTIMIZATION OF A FED-BATCH FERMENTER PRODUCING BAKER’S YEAST USING SIMULATED ANNEALING METHOD,” IRANIAN JOURNAL OF BIOTECHNOLOGY, vol. 7, no. 3, pp. 157–165, 2009, [Online]. Available: https://sid.ir/paper/557039/en

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