DESIGN AND FABRICATION OF BIODEGRADABLE POROUS CHITOSAN/ GELATIN/ TRICALCIUM PHOSPHATE HYBRID SCAFFOLDS FOR TISSUE ENGINEERING

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MOHAMMADI YOUSEF; MIRZADEH HAMID; MOZTARZADEH FATH ELAH; SOLEYMANI MASOUD; JABARI E.

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Journal: Iranian Journal of Polymer Science and Technology Year:2007 | Volume:20 | Issue:3 (ISSUE NO. 89) Page(s): 297-308

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Title

DESIGN AND FABRICATION OF BIODEGRADABLE POROUS CHITOSAN/ GELATIN/ TRICALCIUM PHOSPHATE HYBRID SCAFFOLDS FOR TISSUE ENGINEERING

Author(s)

Keywords

TISSUE ENGINEERINGQ2

POROUS SCAFFOLDQ3

FREEZE-GELATIONQ3

CHITOSANQ3

TRICALCIUM PHOSPHATEQ3

Abstract

In this study, based on a biomimetic approach, novel 3D biodegradable porous hybrid scaffolds consisting of CHITOSAN, gelatin, and TRICALCIUM PHOSPHATE were developed for bone and cartilage TISSUE ENGINEERING. Macroporous CHITOSANlgelatin/b- TCP scaffolds were prepared through the process of FREEZE-GELATION/solid-liquid phase separation. The results showed that the prepared scaffolds are highly porous, with porosities larger than 80%, and have interconnected pores. Biocompatibility studies were successfully performed by in vitro and in vivo assays. Moreover, the attachment, migration, and proliferation of chondrocytes on these unique temporary scaffolds were examined to determine their potentials in TISSUE ENGINEERING applications.

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APA: Copy

MOHAMMADI, YOUSEF, MIRZADEH, HAMID, MOZTARZADEH, FATH ELAH, SOLEYMANI, MASOUD, & JABARI, E.. (2007). DESIGN AND FABRICATION OF BIODEGRADABLE POROUS CHITOSAN/ GELATIN/ TRICALCIUM PHOSPHATE HYBRID SCAFFOLDS FOR TISSUE ENGINEERING. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), 20(3 (ISSUE NO. 89)), 297-308. SID. https://sid.ir/paper/6539/en

Vancouver: Copy

MOHAMMADI YOUSEF, MIRZADEH HAMID, MOZTARZADEH FATH ELAH, SOLEYMANI MASOUD, JABARI E.. DESIGN AND FABRICATION OF BIODEGRADABLE POROUS CHITOSAN/ GELATIN/ TRICALCIUM PHOSPHATE HYBRID SCAFFOLDS FOR TISSUE ENGINEERING. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN)[Internet]. 2007;20(3 (ISSUE NO. 89)):297-308. Available from: https://sid.ir/paper/6539/en

IEEE: Copy

YOUSEF MOHAMMADI, HAMID MIRZADEH, FATH ELAH MOZTARZADEH, MASOUD SOLEYMANI, and E. JABARI, “DESIGN AND FABRICATION OF BIODEGRADABLE POROUS CHITOSAN/ GELATIN/ TRICALCIUM PHOSPHATE HYBRID SCAFFOLDS FOR TISSUE ENGINEERING,” IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), vol. 20, no. 3 (ISSUE NO. 89), pp. 297–308, 2007, [Online]. Available: https://sid.ir/paper/6539/en

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