HYPOGLYCAEMIC EFFECT OF ALCOHOLIC EXTRACT OF TRIGONELLA FOENUM GRACEUM L. (FENUGREEK) SEEDS IN NORMAL AND DIABETIC RATS

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EYDI M.; EYDI A.; SOKHTEH M.

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Paper Information

Journal: JOURNAL OF SCIENCES (ISLAMIC AZAD UNIVERSITY) Year:2006 | Volume:15 | Issue:58/1 (BIOLOGY) Page(s): 452-458

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Title

HYPOGLYCAEMIC EFFECT OF ALCOHOLIC EXTRACT OF TRIGONELLA FOENUM GRACEUM L. (FENUGREEK) SEEDS IN NORMAL AND DIABETIC RATS

Author(s)

EYDI M. | EYDI A. | SOKHTEH M. | Issue Writer Certificate

Keywords

TRIGONELLAFOENUM GRACEUM L.Q4

HYPOGLYCAEMICQ3

DIABETESQ3

RATQ3

Abstract

Seeds of fenugreek (Trigonella foenum graceum L.) are attributed with diuretic, carminative, antidiarrhoeal and antirheumatic effects. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of fenugreek seeds for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic RATs were evaluated. The results showed that orally administration of the alcoholic extract of fenugreek exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic RATs. The extract couldn't change the level of blood glucose and plasma insulin in healthy RATs significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 mg/kg body wt.). The HYPOGLYCAEMIC effect of the extract was more effective than that observed with glibenclamide.

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APA: Copy

EYDI, M., EYDI, A., & SOKHTEH, M.. (2006). HYPOGLYCAEMIC EFFECT OF ALCOHOLIC EXTRACT OF TRIGONELLA FOENUM GRACEUM L. (FENUGREEK) SEEDS IN NORMAL AND DIABETIC RATS. JOURNAL OF SCIENCES (ISLAMIC AZAD UNIVERSITY), 15(58/1 (BIOLOGY)), 452-458. SID. https://sid.ir/paper/70213/en

Vancouver: Copy

EYDI M., EYDI A., SOKHTEH M.. HYPOGLYCAEMIC EFFECT OF ALCOHOLIC EXTRACT OF TRIGONELLA FOENUM GRACEUM L. (FENUGREEK) SEEDS IN NORMAL AND DIABETIC RATS. JOURNAL OF SCIENCES (ISLAMIC AZAD UNIVERSITY)[Internet]. 2006;15(58/1 (BIOLOGY)):452-458. Available from: https://sid.ir/paper/70213/en

IEEE: Copy

M. EYDI, A. EYDI, and M. SOKHTEH, “HYPOGLYCAEMIC EFFECT OF ALCOHOLIC EXTRACT OF TRIGONELLA FOENUM GRACEUM L. (FENUGREEK) SEEDS IN NORMAL AND DIABETIC RATS,” JOURNAL OF SCIENCES (ISLAMIC AZAD UNIVERSITY), vol. 15, no. 58/1 (BIOLOGY), pp. 452–458, 2006, [Online]. Available: https://sid.ir/paper/70213/en

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