THE ANALGESIC ACTIVITY OF HYDROALCHOHOLIC EXTRACTS OF LEAF OF MORINGA OLEIFERA ON CHRONIC CONSTRICTION NERVE INJURY (CCI) IN RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MANAHEJI H.; NAYERI R.; ZARIN GHALAM MOGHADAM JALAL

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Seminar Paper

Paper Information

Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Year:2009 | Issue:19

Download Full-Text

View:

139

Download:

Information Seminar Paper

Title

THE ANALGESIC ACTIVITY OF HYDROALCHOHOLIC EXTRACTS OF LEAF OF MORINGA OLEIFERA ON CHRONIC CONSTRICTION NERVE INJURY (CCI) IN RAT

Author(s)

MANAHEJI H. | NAYERI R. | ZARIN GHALAM MOGHADAM JALAL

Keywords

NEUROPATHIC PAIN SYNDROME

MORINGA OLEIFERA

HYPERALGESIA

GABAPENTIN

Abstract

Neuropathic pain is ambiguous and is reported with different definitions. Until now there is no efficient drug to alleviate the neuropathic pain. Various drugs are used for alleviation of pain. In this research we tried to use Gabapentin and moringa's leaf hydroalcoholic extract for pain relief in an animal model. Wistar male rats weighting 180-220g were used. At first, rats were anesthetized by ketamine and xylazine. CCI induced by Bennett & Xie (1998) model. At 4, 8 and 12 day after surgery, hydroalcoholic extraction of moringa's leaf (200 mg/kg and 400 mg/kg) and Gabapentin (5mg/kg) were injected intraperitoneally. Thermal hyperalgesia and mechanical allodynia were studied and compared with control groups. Gabapentin (5 mg/kg) and moringa 400 mg/kg showed significant reduction of both thermal hyperalgesia and mechanical allodynia in comparison with control groups in all experiments days. Moringa, 200 mg/kg, showed significant reduction only on thermal hyperalgesia at all experimental days. In conclusion, it is recommended that hydroalcoholic extract of moringa leaf to be used alone or along with a drug in alleviation of neuropathic pain syndrome.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

MANAHEJI, H., NAYERI, R., & ZARIN GHALAM MOGHADAM, JALAL. (2009). THE ANALGESIC ACTIVITY OF HYDROALCHOHOLIC EXTRACTS OF LEAF OF MORINGA OLEIFERA ON CHRONIC CONSTRICTION NERVE INJURY (CCI) IN RAT. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/903554/en

Vancouver: Copy

MANAHEJI H., NAYERI R., ZARIN GHALAM MOGHADAM JALAL. THE ANALGESIC ACTIVITY OF HYDROALCHOHOLIC EXTRACTS OF LEAF OF MORINGA OLEIFERA ON CHRONIC CONSTRICTION NERVE INJURY (CCI) IN RAT. 2009. Available from: https://sid.ir/paper/903554/en

IEEE: Copy

H. MANAHEJI, R. NAYERI, and JALAL ZARIN GHALAM MOGHADAM, “THE ANALGESIC ACTIVITY OF HYDROALCHOHOLIC EXTRACTS OF LEAF OF MORINGA OLEIFERA ON CHRONIC CONSTRICTION NERVE INJURY (CCI) IN RAT,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2009, [Online]. Available: https://sid.ir/paper/903554/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops