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Title

EFFECTS OF MAGNESIUM HYDROXIDE ON THE WOUND HEALING IN RAT

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Abstract

 Background: Appropriate treatment and care is essential to acceleration of the healing process, prevention of infection and chronicity of the wound and different means and approaches have thus far been used to this end. The aim of this study was to evaluate the effect of magnesium hydroxide on the wound healing.Methods: The effect of magnesium hydroxide in two model skin wound; length (L) wounds of a 15 mm full-thickness length wound and round (R) wounds of a 5mm diameter full thickness incision were created on the back of rats in the paravertebral area, was evaluated through measuring the length and area of the healed region and process pathological on different days, and conducting tensiometry experiments after complete wound healing.Results: 1. The percentage of wound healing on days 3, 6, 9, 12 and 15 in control (C) group of L wounds changed in the group treated with magnesium hydroxide from 10.13, 31.88, 52.46, 78.75 and 100% to 11.63, 49.75, 94 and 100% respectively; also  the percentage of wound healing on days 3, 6, 9, 12, 15 and 18 in C group of R wounds changed in the group treated with magnesium hydroxide from 9.88, 21.25, 52.13, 69.63, 88.21 and 100% to 12.25, 37.25, 60.5, 76, 93.4 and 100% respectively. 2. Stress changed from 13.19 Newton (N) in the C group of L wound to 20.87 N, also from 11.78 N in the C group of R wound to 16.9 N in group treated with magnesium hydroxide. 3.Strain changed from 9.98 mm in the C group of L wound to 15.43 mm also from 10.53 mm in the C group of L wound to 17 mm in group treated with magnesium hydroxide 4.The results of pathological samples of view histological accelerated in magnesium groups on L and R wounds in partition to C groups.Discussion: Our findings suggest that magnesium hydroxide may have accelerated the skin wound healing in rat and increased tissue strength through stimulating collagen formation.

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    APA: Copy

    ALIZADEH, A.M., MOHAGHEGHI, S.M.A., KHANIKI, M., SAEIDPOUR, KH., & JAFARI, M.. (2007). EFFECTS OF MAGNESIUM HYDROXIDE ON THE WOUND HEALING IN RAT. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/904747/en

    Vancouver: Copy

    ALIZADEH A.M., MOHAGHEGHI S.M.A., KHANIKI M., SAEIDPOUR KH., JAFARI M.. EFFECTS OF MAGNESIUM HYDROXIDE ON THE WOUND HEALING IN RAT. 2007. Available from: https://sid.ir/paper/904747/en

    IEEE: Copy

    A.M. ALIZADEH, S.M.A. MOHAGHEGHI, M. KHANIKI, KH. SAEIDPOUR, and M. JAFARI, “EFFECTS OF MAGNESIUM HYDROXIDE ON THE WOUND HEALING IN RAT,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2007, [Online]. Available: https://sid.ir/paper/904747/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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