SHARDI MANAHEJI FARHAD; RASEKHI ALI REZA

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Seminar Paper

Paper Information

Seminar: CONGREH ANJOMAN UROLOGY IRAN
Year:2005 | Issue:8

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Title

"PERCUTANEOUS ETHANOL INJECTION OF THE PROSTATE FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA"

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Author(s)

SHARDI MANAHEJI FARHAD | RASEKHI ALI REZA

Keywords

ETHANOL

THERAPY

PROSTATIC HYPERPLASIA

PERCUTANEOUS ETHANOL INJECTION

Abstract

PROPOSE: ALTHOUGH T.U.R.P IS THE GOLD STANDARD TREAMENT OF BENIGN PROSTATIC HYPERPLASIA, MINIMALLY INVASIVE PROCEDURES ARE STILL NEEDED, ESPECIALLY IN CASE OF HIGH OPERATIVE RISK PATIENTS. WE WANT TO EVALUATE THE SAFETY AND FEASIBILITY OF A MINIMALLY INVASIVE TREATMENT FOR BPH CONSISTING OF PERCUTANEOUS ETHANOL INJECTION INSIDE THE PROSTATE UNDER TRANSRECTAL ULTRASOUND SURVEILLANCE. METHODS & MATERIALS: IN 10 PATIENTS WHO WERE AFFECTED BY OBSTRUCTIVE BPH TRASPERINEAL ETHANOL INJECTION INTO THE PROSTATE WAS PERFORMED. INJECTIONS WERE PERFORMED UNDER TRANSRECTAL ULTRASOUD AT FOUR SITES OF THE PROSTATE (AT THE BASE AND APEX OF EACH OF THE LATERAL LOBES OF THE PROSTAE) FOR AN OVERALL AMOUNT 6ML OF ETHANANOL PER PATIENT. THE PROCEDURE WAS PERFORMED UNDER LOCAL ANESTHESIA. THEN PEAK FLOW RATE, POST VOID RESIDUAL URINE AND PROSTATIC VOLUME WERE ASSESSED AT 3AND 6 MONTHS AFTER INJECTION AND COMPARED TO PARAMETERS BEFORE INJECTIONS. RESULTS: THE PATIENTS MEDIAN AGE WAS 68.6 (RAGE 59-81). NO MAJOR INTARAOPERATIVE OR POSTOPERATIVE COMPLICATIONS WERE OCCURED. THE MEDIAN PEAK FLOW RATE INCREASED SIGNIFICANTLY FROM 10 ML/S (RANGE 6-15) BEFORE THE PROCEDURE TO 17 ML/S (10-22) AFTER IT AT 3 MONTHS POST INJENTION (P<0.001). THE MEDIAN VOLUME OF POST VOIDING RESIDUAL URINE URINE DROPPED FROM 120 ML (RANGE 50-190) BEFORE TREATMENT TO 25 ML (RANGE 10-39) AFTER IT AT 3 MONTHS AFTER INJECTION (P<0.001). THE SAME PARAMETERS WERE ASSESSED AT 6 MONTHS WITHOUT SIGNIFICANT DIFFERENCES. NO SIGNIFICANT CHANGES WERE SEEN IN VOLUME OF THE GLAND. DISCUSSION & CONCLUSION: PRELIMINARY RESULTS WITH PERCUTANEOUS INJECTION THERAY OF BPH SHOWED SIGNIFICANS IMPROVEMENT OF PEAK URINARY FLOW AND VOLUME OF POST VOIDING RESIDUAL URINE, WITHOUT SEVERE INTRA OR POST OPERATIVE COMPLICATIONS. SIMILAR RESULTS WERE NOTED BY GOYA ET AL. WHO FIRST DESCRIBED ETHANOL INJECTION THERAY OF BPH BY TRANSURETHRAL APPROACH. PERCUTANEOUS TRANSPERINAL ETHANOL INJECTION THERAPY OF BPH IS ASFE, RAPID AND EASY TO PERFORM PROCEDURE. EARLY RESULTS ENCOURAGE FURTHER INVESTIGATIONS IN A LARGER SERIES OF PATIENTS.

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APA: Copy

SHARDI MANAHEJI, FARHAD, & RASEKHI, ALI REZA. (2005). "PERCUTANEOUS ETHANOL INJECTION OF THE PROSTATE FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA". CONGREH ANJOMAN OROLOGY IRAN. SID. https://sid.ir/paper/905265/en

Vancouver: Copy

SHARDI MANAHEJI FARHAD, RASEKHI ALI REZA. "PERCUTANEOUS ETHANOL INJECTION OF THE PROSTATE FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA". 2005. Available from: https://sid.ir/paper/905265/en

IEEE: Copy

FARHAD SHARDI MANAHEJI, and ALI REZA RASEKHI, “"PERCUTANEOUS ETHANOL INJECTION OF THE PROSTATE FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA",” presented at the CONGREH ANJOMAN OROLOGY IRAN. 2005, [Online]. Available: https://sid.ir/paper/905265/en

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