EVALUATION OF CHEMICAL COMPOSITION VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF POLYURETHANE MICROSPHERES PREPARED BY SOLVENT EVAPORATION METHOD

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ORANG FARIBA; RAFIENIA MOHAMMAD

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Seminar Paper

Paper Information

Seminar: IRANIAN CONFERENCE ON BIOMEDICAL ENGINEERING
Year:2004 | Issue:11

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Title

EVALUATION OF CHEMICAL COMPOSITION VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF POLYURETHANE MICROSPHERES PREPARED BY SOLVENT EVAPORATION METHOD

Author(s)

ORANG FARIBA | RAFIENIA MOHAMMAD

Keywords

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Abstract

MICROENCAPSULATION IS ONE OF THE TOOLS FOR CONTROLLED DELIVERY OF THE DRUGS INTO BODY. IN THIS STUDY, POLYURETHANE MICROSPHERES HAVE BEEN SYNTHESIZED BY SOLVENT EVAPORATION METHOD. CASTOR OIL, 4-4-METHYLENE BISPHENYL ISOCYANATE (MDI) AND HEXAMETHYLENDIISOCYANAT (HMDI) ARE USED AS DIOL AND ISOCYANATES. IN THE NEXT STEP, THE EFFECTS OF CHEMICAL COMPOSITIONS VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF PU PARTICLES HAVE BEEN INVESTIGATED. IN ORDER TO EVALUATE THE MORPHOLOGY AND RELEASE BEHAVIOR, FTIR, SEM, OPTICAL MICROSCOPE, DISSOLUTION INSTRUMENT AND UV SPECTROPHOTOMETER HAVE BEEN USED. THE RESULTS SHOW CLEARLY THAT THE POLYMERIZATION REACTIONS HAVE BEEN CARRIED OUT COMPLETELY. THE SURFACE MORPHOLOGY OF THE PARTICLES SEEMED CRIMPLED AS WELL AND THE RELEASE PROFILE INCREASED WITH RISING NCO/OH RATIO.

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APA: Copy

ORANG, FARIBA, & RAFIENIA, MOHAMMAD. (2004). EVALUATION OF CHEMICAL COMPOSITION VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF POLYURETHANE MICROSPHERES PREPARED BY SOLVENT EVAPORATION METHOD. IRANIAN CONFERENCE ON BIOMEDICAL ENGINEERING. SID. https://sid.ir/paper/906425/en

Vancouver: Copy

ORANG FARIBA, RAFIENIA MOHAMMAD. EVALUATION OF CHEMICAL COMPOSITION VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF POLYURETHANE MICROSPHERES PREPARED BY SOLVENT EVAPORATION METHOD. 2004. Available from: https://sid.ir/paper/906425/en

IEEE: Copy

FARIBA ORANG, and MOHAMMAD RAFIENIA, “EVALUATION OF CHEMICAL COMPOSITION VARIATIONS ON RELEASE BEHAVIOR AND MORPHOLOGY OF POLYURETHANE MICROSPHERES PREPARED BY SOLVENT EVAPORATION METHOD,” presented at the IRANIAN CONFERENCE ON BIOMEDICAL ENGINEERING. 2004, [Online]. Available: https://sid.ir/paper/906425/en

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