IMPORTANCE OF IMMORTALIZED CELLS IN BIOBANKING

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ASADI MASOME; MOHAMMADI SHIVA; IZADPANAH MEHRNAZ; SHAHZADE FAZELI ABOLHASSA; FARZANEH PARVANEH

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Seminar Paper

Paper Information

Seminar: CONGRESS OF IRANIAN GENETICS
Year:2014 | Issue:1

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Title

IMPORTANCE OF IMMORTALIZED CELLS IN BIOBANKING

Author(s)

ASADI MASOME | MOHAMMADI SHIVA | IZADPANAH MEHRNAZ | SHAHZADE FAZELI ABOLHASSA | FARZANEH PARVANEH

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Abstract

BIOBANK IS A TYPE OF BIOREPOSITORY WHICH STORES HUMAN BIOLOGICAL SAMPLES FOR USE IN RESEARCH. BIOBANK HAS THREE MAIN OBJECTIVES THAT INCLUDE OF STORAGE OF FROZEN, STANDARD OF CARE AND RESEARCH APPLICATIONS. IN ORDER TO HAVE CONSISTENT MATERIAL THROUGHOUT A RESEARCH PROJECT, RESEARCHERS NEED PRIMARY CELLS WITH AN EXTENDED REPLICATIVE CAPACITY, OR IMMORTALIZED CELLS. SEVERAL METHODS EXIST FOR IMMORTALIZING MAMMALIAN CELLS IN CULTURE, INCLUDE TELOMERASE REVERSE TRANSCRIPTASE GENE OR VIRAL GENES. VIRAL GENES, INCLUDING EPSTEIN-BARR VIRUS, SIMIAN VIRUS 40 T ANTIGEN, ADENOVIRUS E1A AND E1B, AND HUMAN PAPILLOMAVIRUS E6 AND E7 INDUCE IMMORTALIZATION BY A PROCESS KNOWN AS VIRAL TRANSFORMATION. THUS IMMORTALIZED CELLS PROVIDE RESEARCH APPLICATIONS IN BIOBANKS.NOW IRANIAN BIORESOURCE CENTRE (IBRC) IS A BIOBANK WICH ACTIVE IN IMMORTALIZATION CELLS AND STORE THE IMMORTALIZED SAMPLES.

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APA: Copy

ASADI, MASOME, MOHAMMADI, SHIVA, IZADPANAH, MEHRNAZ, SHAHZADE FAZELI, ABOLHASSA, & FARZANEH, PARVANEH. (2014). IMPORTANCE OF IMMORTALIZED CELLS IN BIOBANKING. CONGRESS OF IRANIAN GENETICS. SID. https://sid.ir/paper/906905/en

Vancouver: Copy

ASADI MASOME, MOHAMMADI SHIVA, IZADPANAH MEHRNAZ, SHAHZADE FAZELI ABOLHASSA, FARZANEH PARVANEH. IMPORTANCE OF IMMORTALIZED CELLS IN BIOBANKING. 2014. Available from: https://sid.ir/paper/906905/en

IEEE: Copy

MASOME ASADI, SHIVA MOHAMMADI, MEHRNAZ IZADPANAH, ABOLHASSA SHAHZADE FAZELI, and PARVANEH FARZANEH, “IMPORTANCE OF IMMORTALIZED CELLS IN BIOBANKING,” presented at the CONGRESS OF IRANIAN GENETICS. 2014, [Online]. Available: https://sid.ir/paper/906905/en

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