INVESTIGATION OF PDGF-B (+286) POLYMORPHISM IN PATIENTS WITH MULTIPLE SCLEROSIS AND HEALTHY PEOPLE

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nejati Parham; rezayani Shayesteh

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Seminar Paper

Paper Information

Seminar: INTERNATIONAL MS CONGRESS OF IRAN
Year:2015 | Issue:12

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Title

INVESTIGATION OF PDGF-B (+286) POLYMORPHISM IN PATIENTS WITH MULTIPLE SCLEROSIS AND HEALTHY PEOPLE

Author(s)

nejati Parham | rezayani Shayesteh

Keywords

MULTIPLE SCLEROSIS(MS)

POLYMORPHISM

PDGF-B

Abstract

INTRODUCTION: MULTIPLE SCLEROSIS (MS) IS A CHRONIC DEBILITATING DISEASE OF THE CENTRAL NERVOUS SYSTEM (CNS) IN YOUNG ADULTS WITH OVER TWO MILLION INDIVIDUALS AFFECTED WORLDWIDE. MS IS CAUSED BY IMMUNE CELLS THAT ACTIVATE A CASCADE OF CHEMICALS IN THE BRAIN. THESE CHEMICALS, CALLED CYTOKINES ATTACK TO AND DEGRADE THE MYELIN SHEATH THAT KEEPS NEURONAL SIGNALS MOVING. THESE CYTOKINES DRIVE THE INFLAMMATION IN THE BRAIN AND ATTRACT MORE IMMUNE CELLS, AND CAUSE THE DEBILITATING DISEASE MARKED BY LOSS OF NEUROLOGICAL FUNCTION. DIFFERENT ASSAYS HAVE SHOWN THAT PLATELET DERIVED GROWTH FACTOR BETA (PDGFB) GENE IS ONE OF THE INFLAMMATION INDUCERS THAT IS INVOLVED IN DIFFERENT PATHOLOGICAL CONDITIONS SUCH AS MULTIPLE SCLEROSIS...

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APA: Copy

nejati, Parham, & rezayani, Shayesteh. (2015). INVESTIGATION OF PDGF-B (+286) POLYMORPHISM IN PATIENTS WITH MULTIPLE SCLEROSIS AND HEALTHY PEOPLE. INTERNATIONAL MS CONGRESS OF IRAN. SID. https://sid.ir/paper/921125/en

Vancouver: Copy

nejati Parham, rezayani Shayesteh. INVESTIGATION OF PDGF-B (+286) POLYMORPHISM IN PATIENTS WITH MULTIPLE SCLEROSIS AND HEALTHY PEOPLE. 2015. Available from: https://sid.ir/paper/921125/en

IEEE: Copy

Parham nejati, and Shayesteh rezayani, “INVESTIGATION OF PDGF-B (+286) POLYMORPHISM IN PATIENTS WITH MULTIPLE SCLEROSIS AND HEALTHY PEOPLE,” presented at the INTERNATIONAL MS CONGRESS OF IRAN. 2015, [Online]. Available: https://sid.ir/paper/921125/en

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