THE STUDY OF RELATIONSHIP BETWEEN THE CIRCULATORY NUMBERS OF CELLS EXPRESSING VEGFR1 WITH MULTIPLE SCLEROSIS SEVERITY

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KOUCHAKI EBRAHIM

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Seminar Paper

Paper Information

Seminar: INTERNATIONAL MS CONGRESS OF IRAN
Year:2015 | Issue:12

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Title

THE STUDY OF RELATIONSHIP BETWEEN THE CIRCULATORY NUMBERS OF CELLS EXPRESSING VEGFR1 WITH MULTIPLE SCLEROSIS SEVERITY

Author(s)

KOUCHAKI EBRAHIM

Keywords

MULTIPLE SCLEROSIS

VASCULAR ENDOTHELIAL GROWTH FACTOR

SOLUBLE VEGFR-1

ANGIOGENESIS

Abstract

BACKGROUND: PREVIOUS STUDIES HAVE SHOWN THAT ANGIOGENESIS IS INVOLVED IN PROGRESSION OF CHRONIC INFLAMMATORY DISEASES SUCH AS MULTIPLE SCLEROSIS (MS). ALSO, IT HAS DEMONSTRATED THAT VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) CAN TRIGGER ANGIOGENESIS AS AN ANGIOGENIC FACTOR. IT ACTS THROUGH BINDING TO ITS MEMBRANOUS RECEPTOR VEGFR2 EXPRESSED BY ENDOTHELIAL CELLS. RECENTLY, STUDIES HAVE DEMONSTRATED THAT THERE IS A SOLUBLE FORM OF VEGFR1 (SVEGFR1) IN PLASMA THAT CAN PREVENT THE BINDING OF VEGF TO ITS FUNCTIONAL RECEPTOR ON ENDOTHELIAL CELLS AS A DECOY AND PREVENTS THE CONTINUATION OF ANGIOGENESIS. WE CAN USE IT TO DECREASE THE ANGIOGENESIS AS A KEY METHOD FOR TREATMENT AND DECREASING THE SYMPTOM AND DISABILITY OF SOME INFLAMMATORY DISEASE LIKE MS.

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APA: Copy

KOUCHAKI, EBRAHIM. (2015). THE STUDY OF RELATIONSHIP BETWEEN THE CIRCULATORY NUMBERS OF CELLS EXPRESSING VEGFR1 WITH MULTIPLE SCLEROSIS SEVERITY. INTERNATIONAL MS CONGRESS OF IRAN. SID. https://sid.ir/paper/921191/en

Vancouver: Copy

KOUCHAKI EBRAHIM. THE STUDY OF RELATIONSHIP BETWEEN THE CIRCULATORY NUMBERS OF CELLS EXPRESSING VEGFR1 WITH MULTIPLE SCLEROSIS SEVERITY. 2015. Available from: https://sid.ir/paper/921191/en

IEEE: Copy

EBRAHIM KOUCHAKI, “THE STUDY OF RELATIONSHIP BETWEEN THE CIRCULATORY NUMBERS OF CELLS EXPRESSING VEGFR1 WITH MULTIPLE SCLEROSIS SEVERITY,” presented at the INTERNATIONAL MS CONGRESS OF IRAN. 2015, [Online]. Available: https://sid.ir/paper/921191/en

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