THE EFFECT OF GLYCOGEN SYNTHASE KINASE3 (GSK3) INHIBITOR ON PROLIFERATION OF NEURAL STEM CELLS

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Pachenari Narges; KIANI SAHAR; JAVAN MOHAMMAD

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Seminar Paper

Paper Information

Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Year:2013 | Issue:21

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Title

THE EFFECT OF GLYCOGEN SYNTHASE KINASE3 (GSK3) INHIBITOR ON PROLIFERATION OF NEURAL STEM CELLS

Author(s)

Pachenari Narges | KIANI SAHAR | JAVAN MOHAMMAD

Keywords

ENDOGENOUS NEURAL STEM CELLS

SUBVENTRICULAR ZONE

CHIR99021

Abstract

INTRODUCTION: IN ADULT MAMMALIAN BRAIN, NEURAL STEM CELLS (NSCS) ARE LOCATED IN SUBVENTRICULAR ZONE OF LATERAL VENTRICLES AND SUBGRANULAR ZONE OF DENTATE GYRUS. IN AN INJURED BRAIN, THEY CAN MIGRATE TOWARD THE INJURED SITE TO REPAIR THE DAMAGED TISSUE. BUT THIS REPAIR IS NOT SUFFICIENT ALL THE TIME. THERE ARE MANY SIGNALING PATHWAYS THAT CAN ACTIVATE NEUROGENESIS IN ADULT BRAIN LIKE WNT SIGNALING PATHWAY. CHIR IS A SMALL MOLECULE WHICH CAN MIMIC THIS PATHWAY VIA INHIBITION OF GLYCOGEN SYNTHASE KINASE 3 (GSK3). ...

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APA: Copy

Pachenari, Narges, KIANI, SAHAR, & JAVAN, MOHAMMAD. (2013). THE EFFECT OF GLYCOGEN SYNTHASE KINASE3 (GSK3) INHIBITOR ON PROLIFERATION OF NEURAL STEM CELLS. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/924263/en

Vancouver: Copy

Pachenari Narges, KIANI SAHAR, JAVAN MOHAMMAD. THE EFFECT OF GLYCOGEN SYNTHASE KINASE3 (GSK3) INHIBITOR ON PROLIFERATION OF NEURAL STEM CELLS. 2013. Available from: https://sid.ir/paper/924263/en

IEEE: Copy

Narges Pachenari, SAHAR KIANI, and MOHAMMAD JAVAN, “THE EFFECT OF GLYCOGEN SYNTHASE KINASE3 (GSK3) INHIBITOR ON PROLIFERATION OF NEURAL STEM CELLS,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2013, [Online]. Available: https://sid.ir/paper/924263/en

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