ARTICLE TYPE: REVIEW IMPACT OF HOST GENE POLYMORPHISMS ON SUSCEPTIBILITY TO CHRONIC HEPATITIS B VIRUS INFECTION

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MOUDI BITA; HEIDARI ZAHRA; MAHMOUDZADEH SAGHEB HAMIDREZA

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Seminar Paper

Paper Information

Seminar: CONFERENCE ON UPDATE MANAGEMENT OF HBV AND HCV
Year:2016 | Issue:37

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Title

ARTICLE TYPE: REVIEW IMPACT OF HOST GENE POLYMORPHISMS ON SUSCEPTIBILITY TO CHRONIC HEPATITIS B VIRUS INFECTION

Author(s)

MOUDI BITA | HEIDARI ZAHRA | MAHMOUDZADEH SAGHEB HAMIDREZA

Keywords

HEPATITIS B VIRUS

CYTOKINE

GENETIC

POLYMORPHISM

Abstract

BACKGROUND AND OBJECTIVE: HEPATITIS B VIRUS (HBV) INFECTION CAN RESULT IN A NUMBER OF DIFFERENT CLINICAL CONDITIONS. VARIATIONS IN CYTOKINE GENES HAVE BEEN DISCUSSED TO AFFECT THE NATURAL HISTORY OF HBV INFECTION. VARIOUS STUDIES REVEAL THAT SNPS PLAY AN IMPORTANT ROLE IN PATHOGENESIS OF HBV. ON THE OTHER HAND, VARIOUS OUTCOMES OF INFECTION CANNOT BE COMPLETELY SHOWN BY GENETIC FACTORS BECAUSE THESE STUDIES HAVE INCONSISTENT RESULTS WITH REGARD TO THE POSSIBLE IMPACTS OF HOST GENETIC POLYMORPHISMS ON SUSCEPTIBILITY TO INFECTION.THEREFORE, TO IDENTIFY THE REAL EFFECTS OF HOST GENETIC FACTORS IN HBV SUSCEPTIBILITY AND NATURAL HISTORY OF THE DISEASE, STUDIES WITH LARGE SAMPLE SIZE WILL BE NEEDED. IN ADDITION, DUE TO THE COMPLEX INTERACTIONS OF GENETIC IT IS BETTER TO IDENTIFY SYNERGIES OF SEVERAL SNPS.SUCH STUDIES CAN PROVIDE BETTER INSIGHTS INTO THE NOVEL METHODS OF DIAGNOSIS AND TREATMENT.SEARCH METHOD: HOST IMMUNITY AND GENETIC FACTORS PLAY IMPORTANT ROLES DURING INFECTIONS.CURRENT REVIEW WILL DISCUSS SIGNIFICANT GENETIC VARIATIONS IN CYTOKINE GENES THAT MAY AFFECT THE SUSCEPTIBILITY TO THE CHRONIC HBV INFECTION. THE AIM OF OUR RESEARCH IS TO PROVIDE DIAGNOSTIC MARKERS FOR THE SUSCEPTIBILITY TO HBV INFECTION….

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APA: Copy

MOUDI, BITA, HEIDARI, ZAHRA, & MAHMOUDZADEH SAGHEB, HAMIDREZA. (2016). ARTICLE TYPE: REVIEW IMPACT OF HOST GENE POLYMORPHISMS ON SUSCEPTIBILITY TO CHRONIC HEPATITIS B VIRUS INFECTION. CONFERENCE ON UPDATE MANAGEMENT OF HBV AND HCV. SID. https://sid.ir/paper/924758/en

Vancouver: Copy

MOUDI BITA, HEIDARI ZAHRA, MAHMOUDZADEH SAGHEB HAMIDREZA. ARTICLE TYPE: REVIEW IMPACT OF HOST GENE POLYMORPHISMS ON SUSCEPTIBILITY TO CHRONIC HEPATITIS B VIRUS INFECTION. 2016. Available from: https://sid.ir/paper/924758/en

IEEE: Copy

BITA MOUDI, ZAHRA HEIDARI, and HAMIDREZA MAHMOUDZADEH SAGHEB, “ARTICLE TYPE: REVIEW IMPACT OF HOST GENE POLYMORPHISMS ON SUSCEPTIBILITY TO CHRONIC HEPATITIS B VIRUS INFECTION,” presented at the CONFERENCE ON UPDATE MANAGEMENT OF HBV AND HCV. 2016, [Online]. Available: https://sid.ir/paper/924758/en

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