NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS CLINICAL AND BIOCHEMICAL TOXICITY BIOMARKERS IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES

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MALEKIRAD ALI AKBAR; Mirabdollahi Mansuoreh; FAGHIH MAHYA; Kiani -; FATHI AREZOU; ABDOLLAHI MOHAMMAD

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Seminar Paper

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Seminar: INTERNATIONAL IRANIAN BIOLOGY CONFERENCE
Year:2012 | Issue:17

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Title

NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS CLINICAL AND BIOCHEMICAL TOXICITY BIOMARKERS IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES

Author(s)

Keywords

ORGANOPHOSPHATE

NEUROCOGNITIVE IMPAIRMENT

MENTAL HEALTH STATUS

DIABETES

Abstract

THE AIM OF THIS STUDY WAS TO STUDY TOXICITY OF ORGANOPHOSPHATE (OP) PESTICIDES IN EXPOSED FARMERS IN TERMS OF NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS, CLINICAL SYMPTOM, DIABETES AND HEMATOLOGICAL FACTOR. A COMPARATIVE CROSS-SECTIONAL ANALYSIS WAS DONE IN 174 FARMERS WHO HAVE BEEN EXPOSED OPS IN COMPARISON TO A CONTROL GROUP CONTAINING 174 HEALTHY SUBJECTS WITH THE SAME AGE AND SEX AND EDUCATION LEVEL.THE LEVELS OF FASTING BLOOD GLUCOSE, BLOOD UREA NITROGEN (BUN), CHOLESTEROL, TRIGLYCERIDES, CREATININE, HIGH-DENSITY LIPOPROTEIN (HDL), ASPARTATE AMINOTRANSFERASE (AST) AND ALANINE AMINOTRANSFERASE (ALT) ANDALKALINE PHOSPHATES (ALKP) WERE MEASURED IN THE BLOOD OF SUBJECTS.THE MEAN LEVEL OF FASTING BLOOD GLUCOSE, BUN, CHOLESTEROL AND ALT WAS SIGNIFICANTLY RAISED IN WORKERS WHILECREATININE, TRIGLYCERIDES AND ALKALIN PHOSPHATASE SIGNIFICANTLY DECREASED AS COMPARED WITH CONTROLS. THE MEAN LEVELS OF AST AND FBS2 IN THE WORKERS AND CONTROLS WERE NOT STATISTICALLY DIFFERENT. THE NEUROCOGNITIVE IMPAIRMENT AND PSYCHOLOGICAL DISORDERS WERE SIGNIFICANTLY RAISED IN WORKERS..CLINICAL EXAMINATION WAS DONE IN ORDER TO RECORD ANY ABNORMAL SIGN OR SYMPTOMS. FARMERS SHOWED CLINICAL SYMPTOMS SUCH ASECZEMA, SALIVA SECRETION, FATIGUE, HEADACHE, SWEATING, ABDOMINAL PIAN,, NAUSEA, DISFOGHANI, DISTAHTANI, PROTAHTANI, AZOLATE SHEKAMI, HAND TINGLING, FOOT TINGLING, EPIPHORIA, EDRAR, MYOSIS, DYISPNEA, BRADYCARDIA, NASAL FLOWING. THE PRESENT FINDINGS INDICATE THAT INHIBITION OF ACHE CAN BE INCIDENCE OF NEUROPSYCHOLOGICAL DISORDERS AND PRE DIABETES. USE OF SUPPLEMENTARY ANTIOXIDANTS WOULD BE USEFUL IN THE TREATMENT OF FARMERS.

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APA: Copy

MALEKIRAD, ALI AKBAR, Mirabdollahi, Mansuoreh, FAGHIH, MAHYA, Kiani, -, FATHI, AREZOU, & ABDOLLAHI, MOHAMMAD. (2012). NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS CLINICAL AND BIOCHEMICAL TOXICITY BIOMARKERS IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES. INTERNATIONAL IRANIAN BIOLOGY CONFERENCE. SID. https://sid.ir/paper/928482/en

Vancouver: Copy

MALEKIRAD ALI AKBAR, Mirabdollahi Mansuoreh, FAGHIH MAHYA, Kiani -, FATHI AREZOU, ABDOLLAHI MOHAMMAD. NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS CLINICAL AND BIOCHEMICAL TOXICITY BIOMARKERS IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES. 2012. Available from: https://sid.ir/paper/928482/en

IEEE: Copy

ALI AKBAR MALEKIRAD, Mansuoreh Mirabdollahi, MAHYA FAGHIH, - Kiani, AREZOU FATHI, and MOHAMMAD ABDOLLAHI, “NEUROCOGNITIVE IMPAIRMENT, MENTAL HEALTH STATUS CLINICAL AND BIOCHEMICAL TOXICITY BIOMARKERS IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES,” presented at the INTERNATIONAL IRANIAN BIOLOGY CONFERENCE. 2012, [Online]. Available: https://sid.ir/paper/928482/en

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