THE EFFECT OF ETOMIDATE ON NEUROAPOPTOTIC ALTERATION IN RAT HIPPOCAMPUS

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ALIPOUR MOHAMMAD; KAMKAR ASL MINA; KHORDAD ELNAZ; EBRAHIMI VAHID; EBRAHIMZADEH BIDESKAN ALIREZA

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Seminar Paper

Paper Information

Seminar: GRADUATE CONFERENCE
Year:2016 | Issue:6

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Title

THE EFFECT OF ETOMIDATE ON NEUROAPOPTOTIC ALTERATION IN RAT HIPPOCAMPUS

Author(s)

ALIPOUR MOHAMMAD | KAMKAR ASL MINA | KHORDAD ELNAZ | EBRAHIMI VAHID | EBRAHIMZADEH BIDESKAN ALIREZA

Keywords

ETOMIDATE

HIPPOCAMPUS

APOPTOSIS

ANESTHESIA

NEUROGENESIS

NEURODEGENERATION

Abstract

INTRODUCTION: IN HUMAN BRAINS, THERE ARE SUBSTANTIAL NUMBERS OF NEURONS PRODUCED IN DIFFERENT REGIONS OF HIPPOCAMPUS. NEURON PRODUCTION IS CRITICAL FOR CERTAIN TYPES OF LEARNING AND MEMORY AND COULD BE ALTERED BY CHANGES IN HIPPOCAMPAL CELL PROLIFERATION. FOR EXAMPLE, ANESTHESIA AND SURGERY ARE ASSOCIATED WITH POSTOPERATIVE COGNITIVE CHANGES (I.E., IMPAIRED MEMORY, LEARNING) EVEN LONG AFTER THE ANESTHETIC ITSELF IS GONE. APOPTOSIS, A GRADUAL PROGRAMMED CELL DEATH, IS A MECHANISM THAT POSSIBLY LINKS ANESTHETICS TO THESE IMPAIRMENTS BY SUPPRESSING HIPPOCAMPAL NEUROGENESIS OR INDUCING NEURODEGENERATION. TO TEST THIS HYPOTHESIS, WE INVESTIGATED THE APOPTOTIC EFFECT OF ANESTHESIA WITH ETOMIDATE ON NEURAL CELL APOPTOSIS IN RAT HIPPOCAMPUS...

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APA: Copy

ALIPOUR, MOHAMMAD, KAMKAR ASL, MINA, KHORDAD, ELNAZ, EBRAHIMI, VAHID, & EBRAHIMZADEH BIDESKAN, ALIREZA. (2016). THE EFFECT OF ETOMIDATE ON NEUROAPOPTOTIC ALTERATION IN RAT HIPPOCAMPUS. GRADUATE CONFERENCE. SID. https://sid.ir/paper/929497/en

Vancouver: Copy

ALIPOUR MOHAMMAD, KAMKAR ASL MINA, KHORDAD ELNAZ, EBRAHIMI VAHID, EBRAHIMZADEH BIDESKAN ALIREZA. THE EFFECT OF ETOMIDATE ON NEUROAPOPTOTIC ALTERATION IN RAT HIPPOCAMPUS. 2016. Available from: https://sid.ir/paper/929497/en

IEEE: Copy

MOHAMMAD ALIPOUR, MINA KAMKAR ASL, ELNAZ KHORDAD, VAHID EBRAHIMI, and ALIREZA EBRAHIMZADEH BIDESKAN, “THE EFFECT OF ETOMIDATE ON NEUROAPOPTOTIC ALTERATION IN RAT HIPPOCAMPUS,” presented at the GRADUATE CONFERENCE. 2016, [Online]. Available: https://sid.ir/paper/929497/en

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