GRADUATE CONFERENCE | Year:2016 | دوره:6 |Papers Count:40

INTRODUCTION: OXIDATIVE STRESS DUE TO HYPERGLYCEMIA IS A MAJOR CAUSE OF DIABETES COMPLICATIONS. THE AIM OF THIS STUDY WAS TO EVALUATE THE EFFECTS OF POMEGRANATE SEED OIL (PSO) ON SERUM BIOCHEMICAL PARAMETERS, CARDYOMYOPATHY AND NEPHROPATHY- INDUCED BY DIABETES MELLITUS.

FREE RADICAL INDUCED NEURAL DAMAGE IS CONCERNED IN BRAIN ISCHEMIA AND ANTIOXIDANTS ARE REPORTED TO HAVE NEUROPROTECTIVE ACTIVITY. THE PRESENT STUDY WAS DESIGNED TO ASSESS THE NEUROPROTECTIVE ROLE OF RUTIN, PINE BARK, ALOE VERA AND CELERY...

INTRODUCTION: DIABETES IS THE MOST COMMON DISEASES CAUSED BY METABOLIC DISORDER AND THE LEADING CAUSE OF DEATH IN WESTERN SOCIETIES. THE PATHOGENESIS OF THIS COMPLICATION IS VERY HIGH BOTH IN TERMS OF MEDICAL COSTS AND DISABILITY AND IT IS ONE OF THE MAJOR ISSUES IN HUMAN HEALTH. ONE OF THE MOST EFFECTIVE MEASURES TO PREVENT THIS DISEASE IS TO PREDICT DISEASE RISK IN SUSCEPTIBLE HEALTHY PEOPLE. GIVEN THE APPLICATION OF DATA MINING METHODS AND THEIR ABILITY IN MATTERS OF CLASSIFICATION, NOWADAYS THESE METHODS ARE USED IN VARIOUS FIELDS. THEREFORE, IN THIS STUDY IT HAS BEEN ATTEMPTED TO ADDRESS THE DATA MINING METHODS TO PREDICT THIS DISEASE...

INTRODUCTION: IN HUMAN BRAINS, THERE ARE SUBSTANTIAL NUMBERS OF NEURONS PRODUCED IN DIFFERENT REGIONS OF HIPPOCAMPUS. NEURON PRODUCTION IS CRITICAL FOR CERTAIN TYPES OF LEARNING AND MEMORY AND COULD BE ALTERED BY CHANGES IN HIPPOCAMPAL CELL PROLIFERATION. FOR EXAMPLE, ANESTHESIA AND SURGERY ARE ASSOCIATED WITH POSTOPERATIVE COGNITIVE CHANGES (I.E., IMPAIRED MEMORY, LEARNING) EVEN LONG AFTER THE ANESTHETIC ITSELF IS GONE. APOPTOSIS, A GRADUAL PROGRAMMED CELL DEATH, IS A MECHANISM THAT POSSIBLY LINKS ANESTHETICS TO THESE IMPAIRMENTS BY SUPPRESSING HIPPOCAMPAL NEUROGENESIS OR INDUCING NEURODEGENERATION. TO TEST THIS HYPOTHESIS, WE INVESTIGATED THE APOPTOTIC EFFECT OF ANESTHESIA WITH ETOMIDATE ON NEURAL CELL APOPTOSIS IN RAT HIPPOCAMPUS...

INTRODUCTION: MAJORITY OF COLORECTAL CARCINOMAS (CRCS) ARISE FROM ADENOMATOUS POLYPS. ONE APPROACH TO PREVENTION IS BASED ON RECOGNITION AND REMOVAL OF POLYPS. THE DISTRIBUTION OF POLYPS IN THE COLON MAY AFFECT THE EFFICACY OF SCREENING MODALITIES. THE AIM OF THIS STUDY WAS TO DETERMINE PATHOLOGY CHARACTERISTICS OF COLORECTAL POLYPS IN THE NORTHEAST IRAN...

INTRODUCTION: THE MECHANISTIC/MAMMALIAN TARGET OF RAPAMYCIN (MTOR) IS A SER/THR KINASE, THE KEY DOWNSTREAM EFFECTOR OF PI3K PATHWAY THAT CONTROLS SEVERAL ANABOLIC PROCESSES IN CELL GROWTH AND PROLIFERATION. DYSREGULATION OF THIS GENE HAS BEEN IMPLICATED IN SEVERAL DISEASES, INCLUDING CANCERS. MICRORNAS (MIR) ARE SMALL-NON-CODING AND SINGLE STRAND RNAS THAT INHIBIT PROTEIN TRANSLATION BY TARGETING THE 3’-UTR OF MRNA. THERE ARE TWO TYPES OF MIR: ONCO MIR AND TUMOR SUPPRESSOR MIR. AS WITH PREVIOUS, DYSREGULATION IN MIR ALSO IS BEING SEEN IN MANY OF CANCERS.

INTRODUCTION: ACRYLAMIDE (ACR) IS A WATER-SOLUBLE MONOMER THAT IS USED IN DIFFERENT INDUSTRIES AND HAS BEEN FOUND IN CARBOHYDRATE RICH FOOD COOKED AT HIGH TEMPERATURES. ACR MONOMER IS A POTENT NEUROTOXIC AGENT AND DAMAGES THE CENTRAL AND THE PERIPHERAL NERVOUS SYSTEM IN HUMAN AND ANIMALS...

INTRODUCTION: DIABETES IS ONE OF THE CHRONIC DISEASES WITH NO CURATIVE TREATMENT; ALSO, IT IS THE MOST COMMON CAUSE OF AMPUTATION, BLINDNESS AND CHRONIC RENAL FAILURE AND THE MOST IMPORTANT RISK FACTOR OF HEART DISEASES. LOGISTIC REGRESSION IS ONE OF THE STATISTICAL ANALYSIS MODELS FOR PREDICTING THAT CAN BE USED TO FIND OUT THE RELATIONSHIP BETWEEN DEPENDENT AND PREDICTOR INDEPENDENT VARIABLES AND CONTROL OF THE CONFOUNDING VARIABLES. THE AIM OF THIS STUDY WAS TO ESTIMATE THE ASSOCIATION OF DIABETES WITH BODY MASS INDEX (BMI), WAIST TO HIP RATIO (WHR), AND WAIST CIRCUMFERENCE (WC) IN THE POPULATION OF MASHHAD AGED 35 TO 64 YEARS...

INTRODUCTION: THERE ARE EVIDENCE REGARDING ANTI-INFLAMMATORY AND ANTICANCER EFFECT OF EXERCISE. HOWEVER, THE AIRWAY RESPONSE TO EXERCISE IN ATHLETES POPULATION HAS BEEN POORLY INVESTIGATED ESPECIALLY IN WOMEN. IN THE PRESENT STUDY PULMONARY FUNCTION TEST CHANGES IN PHYSICALLY FIT FEMALE STUDENTS WAS EXAMINED...

INTRODUCTION: INFLAMMATION AND OXIDATIVE STRESS IS CONSIDERED TO HAVE A CRUCIAL ROLE IN INDUCTION OF NEPHROPATHY. CURCUMA LONGA (C. LONGA) AND NIGELLA SATIVA (N. SATIVA) HAVE ANTI-INFLAMMATORY AND ANTIOXIDANT EFFECTS. THIS STUDY WAS DESIGNED TO INVESTIGATE THE EFFECT OF MIXED HYDRO-ALCOHOLIC EXTRACT OF N.SATIVA AND C. LONGA ON THE OXIDATIVE STRESS INDUCED BY ADRIAMYCIN (ADR) IN RAT KIDNEY.

INTRODUCTION: THE POSITIVE ROLES OF ANTIOXIDANTS ON BRAIN DEVELOPMENT AND LEARNING AND MEMORY HAVE BEEN SUGGESTED. NIGELLA SATIVA (NS) HAS BEEN SUGGESTED TO HAVE ANTIOXIDANT AND NEUROPROTECTIVE EFFECTS. THIS STUDY WAS DONE TO INVESTIGATE THE EFFECTS FEEDING BY THE HYDRO-ALCOHOLIC EXTRACT OF NS DURING NEONATAL AND JUVENILE GROWTH ON LEARNING AND MEMORY OF RATS...

INTRODUCTION: SMALL UBIQUITIN-LIKE MODIFIER (SUMO) ARE A FAMILY OF UBIQUITIN LIKE PROTEINS THAT ARE INVOLVED IN WIDE VARIETY OF SIGNALLING PATHWAYS. SUMOYLATION AS A POST TRANSLATIONAL MODIFICATION IS WELL KNOWN IN EUKARYOTIC CELLS. THE AIM OF THIS STUDY WAS TO INVESTIGATE SUMOYLATION PATTERN OF PROTEINS AFTER INTOXICATION WITH DIAZINON AND CO ADMINISTRATION OF CROCIN AS A PROTECTIVE COMPOUND...

INTRODUCTION: IN THE PRESENT STUDY, WE AIMED TO EXAMINE THE POTENTIAL PROTECTIVE EFFECTS OF THYMOQUINONE (TQ) ON SPATIAL AND NON -SPATIAL MEMORY IMPAIRMENT INDUCED BY SCOPOLAMINE (SCO) AND THE BRAIN TISSUES OXIDATIVE DAMAGE IN RATS...

INTRODUCTION: THE LIVER IS THE BODY'S MOST IMPORTANT ORGANISMS. NOW, CHRONIC LIVER DISEASE IS AN IMPORTANT CAUSE OF DEATHS IN THE WORLD. CELL LINES HUH7.5 IS A HUMAN HEPATOMA CELL LINE THAT DERIVED FROM HUH7 CELLS. NIGELLA SATIVA PLANT SHOWED PROTECTIVE EFFECTS ON LIVER DISEASES. THIS PLANT HAS THYMOQUINONE (TQ) COMPOUND WITH ANTI-FIBROSIS EFFECT ON LIVER AND IT HAS SOME OTHER FUNCTIONS SUCH AS ANTI-INFLAMMATORY, ANALGESIC, ANTI-TUMOR, ANTIBACTERICIDAL, WOUND HEALING AS WELL. THIS STUDY CONDUCTED TO EVALUATE THE EFFECTS OF NIGELLA SATIVA PLANT EXTRACTION ON HEPATITIS C VIRUS REPLICATION IN CELL CULTURE SYSTEM.

INTRODUCTION: SOME FACTORS LED TO THE DESERTION OF FAMILY PHYSICIANS FORM THEIR WORK IN THE RURAL AREAS OF IRAN. THE AIM OF THIS STUDY IS TO DETERMINE THE RELATIONSHIP BETWEEN THE QUALITY OF WORK LIFE AND FACTORS THAT CAUSES THE PHYSICIANS TO LEAVE FORM THE FAMILY PHYSICIAN PROGRAM...

INTRODUCTION: THERE IS A LACK OF DATA ON FAMILIAL AGGREGATION OF COLORECTAL CANCER (CRC) IN NORTHEAST OF IRAN. WE AIMED TO DETERMINE THE FREQUENCY OF HEREDITARY NONPOLYPOSIS COLORECTAL CANCER (HNPCC) AND FAMILIAL COLORECTAL CANCER (FCC) AND TO DETERMINE THE FREQUENCY OF EXTRACOLONIC CANCERS IN THESE FAMILIES IN MASHHAD.

INTRODUCTION: A-HEDERIN IS ONE OF PRINCIPAL BIOACTIVE CONSTITUENTS OF NIGELLA. SATIVA AND HEDERA HELIX. IN THE PRESENT STUDY, THE PREVENTIVE EFFECT OF TWO DIFFERENT CONCENTRATIONS OF A-HEDERIN ON TRACHEAL RESPONSIVENESS, LUNG INFLAMMATION AND BLOOD CYTOKINES IN OVALBUMIN SENSITIZED GUINEA PIGS WAS EXAMINED...

INTRODUCTION: PRESENCE OF HLA-DQ2 AND HLA-DQ8 ALLELES IN THE INFECTED INDIVIDUALS IS ONE OF THE IMPORTANT GENETIC FACTORS IN THE DEVELOPMENT OF CELIAC DISEASE (CD). MANY MOLECULAR TECHNIQUES ARE AVAILABLE TO DETERMINE THESE ALLELES, BUT THESE METHODS HAVE MANY STEPS THAT MAKE THEM DIFFICULT TO USE, THEREFORE THE AIM OF THIS STUDY WAS TO SET UP A SIMPLE AND QUICK REALTIME PCR BASED SYBR Ò GREEN METHOD TO DETERMINE THE HLA-DQ ALLELES IN PATIENTS WITH CD...

INTRODUCTION: ANALGESIC, ANTI-INFLAMMATORY AND HYPNOTIC EFFECTS OF ROSA DAMASCENA HAS BEEN WIDELY INVESTIGATED. IN THE PRESENT STUDY THE EFFECTS OF AQUEOUS, ETHANOLIC AND CHLOROFORMIC EXTRACTS OF ROSA DAMASCENA ON PTZ INDUCED SEIZURES WERE INVESTIGATED IN MICE...

INTRODUCTION: IN THIS STUDY, IN VITRO DRUG RELEASE BEHAVIOR FROM IN SITU FORMING IMPLANTS CONSISTING OF PLGA, NALTREXONE OR NALTREXONE HYDROCHLORIDE, AND EXIPIENT DISSOLVED IN 1-METHYL-2-PYRROLIDONE (NMP) INVESTIGATED...

INTRODUCTION: ONE OF THE MAJOR PATHS FOR DRUG DEVELOPMENT IS THE STUDY OF BIOACTIVITIES OF NATURAL PRODUCTS. THEREFORE, THE AIM OF THIS STUDY WAS TO COMPARE THE CYTOTOXIC EFFECTS OF AQUEOUS EXTRACT OF WHOLE RHEUM TURKESTANICUM, WHICH IS A TRADITIONAL MEDICINAL HERB COMMONLY USED IN IRAN AND OTHER ORIENTAL COUNTRIES, ON THE HUMAN ACUTE MYELOBLASTIC LEUKEMIA (HL60) AND ANOTHER HUMAN LYMPHOCYTE JURKAT (JM) CELL LINES...

INTRODUCTION: THE AIM OF THIS STUDY WAS TO INVESTIGATE THE EFFECTS OF TAMOXIFEN AND SOY ON HIPPOCAMPUS AND DENTATE GYRUS APOPTOSIS IN OVARIECTOMIZED RATS AFTER REPEATED SEIZURES...

INTRODUCTION: A BLACK KIDNEY HAS 3 MAJOR DIFFERENTIAL DIAGNOSES: HEMOSIDEROSIS, LIPOFUSCIN PIGMENT AND MELANOTIC RENAL CELL CARCINOMA. EXCLUDING LIPOFUSCIN, THE OTHER 2 ARE ACCOMPANIED BY AN ABNORMAL RENAL FUNCTION...

INTRODUCTION: DIABETES IS ONE OF MOST COMMON CHRONIC AND NONCOMMUNICABLE DISEASE, WITH MANY COMPLICATIONS INCLUDING RENAL FAILURE, BLINDNESS AND NON-TRAUMATIC AMPUTATION. PREVENTION DIABETES OF IS POSSIBLE THROUGH MONITORING AND CONTROL OF BLOOD GLUCOSE LEVELS. REFERENCE PLOTS ARE USED TO SCREEN THOSE WITH ABNORMAL FASTING BLOOD SUGAR (FBS). THE PROBLEM IS THAT A REFERENCE PLOT DERIVED IN A SPECIFIC POPULATION CANNOT BE EFFICIENTLY USED IN OTHER POPULATION WITH DIFFERENT CHARACTERISTICS. THE RATIONAL IS THAT PEOPLE ARE COMPARED WITH THEIR POPULATION FBS VALUES. THE PRESENT STUDY AIMED TO FIGURE OUT THE REFERENCE PLOTS FOR FBS IN THE POPULATION OF MASHHAD AGED 35 TO 64 YEARS...

INTRODUCTION: CARDIOVASCULAR DISEASE IS THE MAJOR REASON OF MORTALITY AND MORBIDITY IN THE WORLD. IN ADDITION TO ABNORMAL LEVELS OF LDLC, CHOLESTEROL, THE OXIDATIVE STRESS HAS BEEN BELIEVED TO BE ONE OF THE MAJOR RISK FACTORS FOR CARDIOVASCULAR DISEASE. IN SOME COUNTRIES IN ASIA OLDER PEOPLE BELIEVE THAT OPIUM REDUCES TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS. THIS DRUG HAS BEEN TRADITIONALLY USED IN IRAN FOR HAPPINESS OR AS A HEALING FOR MANY DISEASES SUCH AS DIARRHEA, PAIN AND INSOMNIA. THE AIM OF THE PRESENT EXPERIMENT WAS TO ASSESS THE EFFECT OF OPIUM ON LIPID PROFILES, LIPID PEROXIDATION, ANTIOXIDANT ACTIVITY AND LIVER ENZYMES...

INTRODUCTION: THE RELAXANT EFFECT OF PORTULACAOLERACEAL. (P. OLERACEA) ON TRACHEAL SMOOTH MUSCLES (TSM) HAS BEEN SHOWN...

INTRODUCTION: APTAMERS ARE SINGLE STRANDED DNA OR RNA SEQUENCES, OBTAINED BY AN IN VITRO PROCESS CALLED SELEX (SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT). THEY REACT TO THEIR TARGETS WITH HIGH SPECIFICITY AND AFFINITY. APTAMERS HAVE HIGH POTENTIAL APPLICATIONS IN MEDICINE BECAUSE OF THEIR UNIQUE PROPERTIES SUCH AS LOW COST, EASE OF PRODUCTION AND MODIFICATION, EXCELLENT THERMAL STABILITY, AND LACK OF IMMUNOGENICITY AND TOXICITY.

INTRODUCTION: THE GENUS FERULA (APIACEAE) COUNTS APPROX 185 SPECIES. SEVERAL SPECIES, SUCH AS F. GUMMOSA, F. ASAFETIDA AND F. LATISECTA HAVE BEEN USED IN FOLK MEDICINE TO TREAT COLITIS IN INFANTS AND ASTHMA. THE GENUS FERULA IS KNOWN TO BE A RICH SOURCE OF BIOLOGICALLY ACTIVE COMPOUNDS, SUCH AS SESQUITERPENES AND COUMARINS THAT ARE OF PARTICULAR INTEREST DUE TO THEIR BROAD RANGE OF REPORTED ACTIVITIES, SUCH AS ANTIBACTERIAL, ANTI-INFLAMMATORY, ANTI-HIV, ANTIPROTOZOA AND CYTOTOXIC PROPERTIES. FERULA PSEUDALLIACEA RECH.F. IS AN INDIGENOUS SPECIES OF THE KURDISTAN MOUNTAINS IN WESTERN IRAN. WE REPORT ON THE IDENTIFICATION OF A NEW SESQUITERPENE COUMARINS AND ON ITS IN VITRO ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYLORI AND STAPHYLOCOCCUS AUREUS AS WELL AS CYTOTOXIC ACTIVITY IN HELA CELL...

INTRODUCTION: KELUSSIA ODORATISSIMA MOZAFF. (APIACEAE) IS AN EDIBLE, INDIGENOUS AND ETHNOMEDICINAL PLANT, WHICH ONLY GROWS IN IRAN. IN SPITE OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES, CYTOTOXIC ACTIVITY OF THIS PLANT HAS NOT BEEN PREVIOUSLY INVESTIGATED. THE AIM OF THIS STUDY WAS TO EVALUATE THE CYTOTOXICITY OF K. ODORATISSIMA LEAF EXTRACT AGAINST A PANEL OF HUMAN CANCER CELL LINES. THE SECONDARY AIM WAS TO PERFORM A PHYTOCHEMICAL ANALYSIS OF THE PLANT’S LEAF OIL...

INTRODUCTION: CHRONIC KIDNEY DISEASE (CKD), A WORLDWIDE EPIDEMIC, IS A COMPLEX DISORDER WITH HIGH SOCIOECONOMIC COST. THE DIETARY APPROACHES TO STOP HYPERTENSION (DASH) DIET IS A WELL-ESTABLISHED OVERALL DIETARY PATTERN WITH COMPONENTS, WHICH HAS BEEN IDENTIFIED AS POTENTIAL RISK FACTORS. THIS STUDY WAS CONDUCTED TO EXAMINE THE ASSOCIATION BETWEEN ADHERENCE TO THE DASH SCORE AND INCIDENT CKD AMONG AN IRANIAN POPULATION...

INTRODUCTION: INFECTION IS AN IMPORTANT CAUSE OF MORTALITY IN BURNS. IT HAS BEEN ESTIMATED THAT 75% OF ALL DEATHS FOLLOWING THERMAL INJURIES ARE RELATED TO INFECTIONS. THE RATE OF NOSOCOMIAL INFECTIONS ARE HIGHER IN BURN PATIENTS DUE TO VARIOUS FACTORS LIKE NATURE OF BURN INJURY ITSELF, IMMUNOCOMPROMISED STATUS OF THE PATIENT, INVASIVE DIAGNOSTIC AND THERAPEUTIC PROCEDURES AND PROLONGED ICU STAY. THE STUDY WAS CARRIED OUT TO DETERMINE THE BACTERIAL PROFILE AND ANTIMICROBIAL SUSCEPTIBILITY OF THE ISOLATES AND TO DESCRIBE THE CHANGE IN TRENDS OVER THE STUDY PERIOD.

INTRODUCTION: RENIN-ANGIOTENSIN SYSTEM HAS A ROLE IN INFLAMMATION AND ALSO INVOLVES IN MANY BRAIN FUNCTIONS SUCH AS LEARNING, MEMORY AND EMOTION. NEURO-IMMUNE FACTORS HAVE BEEN PROPOSED AS THE CONTRIBUTORS TO THE PATHOGENESIS OF MEMORY IMPAIRMENTS. IN THE PRESENT STUDY, THE EFFECT OF CAPTOPRIL ON SPATIAL MEMORY AND SYNAPTIC PLASTICITY IMPAIRMENT INDUCED BY LIPOPOLYSACCHARIDE (LPS) WAS INVESTIGATED IN RATS

INTRODUCTION: AN IMPORTANT ROLE FOR OXIDATIVE STRESS, AS A CONSEQUENCE OF EPILEPTIC SEIZURES HAS BEEN SUGGESTED. REGARDING THE ANTIOXIDANT EFFECTS OF PINUS ELDARICA, THE EFFECTS OF THE PLANT EXTRACT ON THE BRAIN TISSUES OXIDATIVE DAMAGES FOLLOWING SEIZURES INDUCED BY PENTYLENETETRAZOLE (PTZ) WAS INVESTIGATED...

INTRODUCTION: BREAST CANCER IS THE MOST COMMON WITH A POOR PROGNOSIS. THERE IS A GROWING BODY OF DATA INDICATING THE ANTITUMOR ACTIVITY OF CURCUMIN IN DIFFERENT TUMOR TYPES. THE AIM OF THE CURRENT STUDY WAS TO EXPLORE THE CYTOTOXIC EFFECT OF CURCUMIN IN TWO- AND THREE-DIMENSIONAL MODELS OF MCF-7...

INTRODUCTION: SKILL IS DEFINED AS THE PROPER AND SUPPLY THE USE OF THE SCIENCE. TODAY, TEACHING LIFE SKILLS IS CONSIDERED AS AN ESSENTIAL PART OF SOCIABILITY. IMPROVING THE MENTAL STATUS AND SOCIAL SKILLS OF MEDICAL STUDENTS WILL PLAY A CRUCIAL ROLE IN THEIR PSYCHOSOCIAL HEALTH STATUS. THE AIM OF THIS STUDY IS TO EVALUATE THE LIFE SKILLS OF MEDICAL STUDENTS IN MASHHAD UNIVERSITY OF MEDICAL SCIENCES (MUMS)...

INTRODUCTION: LEISHMANIA SPECIES WHICH BELONGS TO KINETOPLASTIDE FAMILY MUST DEFEND SELF AGAINST FREE RADICALS TO SURVIVE IN HOST MACROPHAGES. IRON- SUPEROXIDE DISMUTASE (FE-SOD) IS AN ANTIOXIDANT ENZYME IN LEISHMANIA SPP, WHICH PREVENT CELLULAR OXIDATIVE DAMAGES...

INTRODUCTION: THE POSITIVE ROLES OF ANTIOXIDANTS ON THE BRAIN DEVELOPMENT AND LEARNING AND MEMORY HAVE BEEN SUGGESTED. VITAMIN C (VIT C) HAS BEEN SUGGESTED TO HAVE ANTIOXIDANT AND NEUROPROTECTIVE EFFECTS. THIS STUDY WAS DONE TO INVESTIGATE THE EFFECTS FEEDING BY VIT C DURING NEONATAL AND JUVENILE GROWTH ON LEARNING AND MEMORY OF RATS...

INTRODUCTION: COCAINE IS ONE OF THE MOST COMMONLY ABUSED STIMULANT WHICH COULD AFFECT THE CENTRAL NERVOUS SYSTEM. THE SENSITIVE DETECTION OF COCAINE IS ESSENTIAL FOR CLINICAL DIAGNOSIS AND LAW ENFORCEMENT. APTAMERS ARE SHORT SINGLE-STRANDED OLIGONUCLEOTIDES, SELECTED BY AN IN VITRO PROCESS CALLED SELEX (SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT). APTAMERS BIND TO THEIR PRE-SELECTED TARGETS, RANGING FROM SMALL SUBSTANCES TO CELLS WITH HIGH SPECIFICITY AND AFFINITY. IN THIS WORK, AN ELECTROCHEMICAL APTASENSOR WAS DESIGNED FOR SENSITIVE AND SELECTIVE DETECTION OF COCAINE, BASED ON COMPLIMENTARY STRANDS OF APTAMER (CSS), H-SHAPE STRUCTURE OF APTAMER (APT) - CSS CONJUGATE AND GOLD ELECTRODE...

INTRODUCTION: URBANIZATION BEHAVIOR HAS AN IMPORTANT ROLE IN EPIDEMIOLOGIC TRANSITION OF ILLNESSES AND AS A RESULT, THE HEALTH TRANSITION. URBANIZATION HAS A MAJOR ROLE IN INCREASING EXPOSURE LEVEL WITH RISK FACTORS WHICH INCREASE THE NON-COMMUNICABLE DISEASES. THIS STUDY WAS CONDUCTED TO EXAMINE THE RELATIONSHIP BETWEEN URBANIZATION AND RISK FACTORS OF NON-COMMUNICABLE DISEASES, ACCORDING TO THE STEP BY STEP PROCEDURE OF WORLD HEALTH ORGANIZATION (STEP WISE 2011).

INTRODUCTION: HIGH SUGAR-SWEETENED BEVERAGE (SSB) CONSUMPTION IS ASSOCIATED WITH CARDIO-METABOLIC DISTURBANCES, URECEMIA, AND ALBUMINURIA IN ADULTS; HOWEVER, THERE ARE CURRENTLY LIMITED STUDIES ON SSBS AND CHRONIC KIDNEY DISEASE (CKD). OUR OBJECTIVE WAS TO EVALUATE CROSS-SECTIONAL AND LONGITUDINAL RELATIONSHIPS BETWEEN SSB, CARBONATED BEVERAGE, AND FRUIT JUICE CONSUMPTION AND RISK OF CKD IN A POPULATION BASED STUDY...