مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Seminar Paper

Title

TOXICITY AND OXIDATIVE STRESS OF BI2O3 NANOPARTICLES

Pages

  -

Abstract

 BISMUTH COMPOUNDS ARE USED IN COSMETICS, PIGMENTS, AND A FEW PHARMACEUTICALS, NOTABLY BISMUTH SUBSALICYLATE, USED TO TREAT DIARRHOEA. ACUTE TOXICITY OF BI2O3 NANOPARTICLES (BI2O3-NP, 60 NM) WAS EVALUATED IN RAT AS A BIOLOGICAL MODEL. ONE GROUP OF FIVE MALE RATS WAS ORALLY ADMINISTERED BI2O3-NP, ONCE A DAY FOR 15 DAYS WITH DOSE OF 80 MG/KG, BODY WEIGHT. A CONTROL GROUP WAS ALSO MADE OF FIVE RATS. BI2O3-NP EXPOSURE INCREASED THE INDUCTION OF REACTIVE OXYGEN SPECIES (ROS), A SIGNIFICANT DECREASE IN BLOOD AMINOLEVULINIC ACID DEHYDRATASE (ALAD) ACTIVITY AND GLUTATHIONE (GSH) LEVEL. BASED ON THESE RESULTS, IT IS SUGGESTED THAT SHORT-TERM ADMINISTRATION OF HIGH DOSES OF BI2O3-NP MAY CAUSE ORGAN TOXICITY AND OXIDATIVE STRESS.

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    • Cite

    APA: Copy

    AMIRI, ASGHAR. (2017). TOXICITY AND OXIDATIVE STRESS OF BI2O3 NANOPARTICLES. CONFERENCE ON THE DEVELOPMENT OF SCIENCE AND CHEMICAL INDUSTRY. SID. https://sid.ir/paper/933747/en

    Vancouver: Copy

    AMIRI ASGHAR. TOXICITY AND OXIDATIVE STRESS OF BI2O3 NANOPARTICLES. 2017. Available from: https://sid.ir/paper/933747/en

    IEEE: Copy

    ASGHAR AMIRI, “TOXICITY AND OXIDATIVE STRESS OF BI2O3 NANOPARTICLES,” presented at the CONFERENCE ON THE DEVELOPMENT OF SCIENCE AND CHEMICAL INDUSTRY. 2017, [Online]. Available: https://sid.ir/paper/933747/en

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