IMPACT OF COLON CANCER STEM CELLS ON IMMUNE RESPONSE BY PERIPHERAL BLOOD MONONUCLEAR CELLS

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Mohebi Ashtiani Bahareh; BAGHAEI KAVEH; HASHEMI MEHRDAD; Beigi Samaneh

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Seminar Paper

Paper Information

Seminar: INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS
Year:2016 | Issue:3

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Title

IMPACT OF COLON CANCER STEM CELLS ON IMMUNE RESPONSE BY PERIPHERAL BLOOD MONONUCLEAR CELLS

Author(s)

Mohebi Ashtiani Bahareh | BAGHAEI KAVEH | HASHEMI MEHRDAD | Beigi Samaneh

Keywords

HT-29

PBMNCS

MONOCYTE

M1 MACROPHAGE

IL-6

IL-12B

TNF-α

Abstract

INTRODUCTION AND AIM: SOLUBLE FACTORS, CHEMOKINES AND CYTOKINES OF TUMOR CELLS LEAD TO INFLAMMATION, AND THE CELLS RECRUITED TO THE TUMOR MICROENVIRONMENT ARE MACROPHAGE AND MAST CELLS. STUDIES INDICATE THAT INFLAMMATION ACCELERATES TUMOR PROGRESSION. ON THE OTHER HAND, IMMUNE CELLS CAN ALSO INCREASE ANTI-TUMOR IMMUNITY. EXISTENCE OF THE IMMUNE CELLS AND SOLUBLE FACTORS MAINTAIN A BALANCE BETWEEN TUMOR PROMOTING INFLAMMATION AND ANTI-TUMOR IMMUNITY. MACROPHAGE INFILTRATION HAS BEEN ASSOCIATED WITH POOR PROGNOSIS IN DIFFERENT CANCERS, SUCH AS BREAST CANCER, AND CERVICAL CANCER. BUT AT THE INVASIVE STAGES OF COLORECTAL CANCER, IT WAS ASSOCIATED WITH IMPROVED PROGNOSIS. IN THIS STUDY, EFFECT OF COLORECTAL CANCER STEM CELL (HT-29) IN AN IMMUNE RESPONSE PRODUCED BY PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMNCS) WAS EVALUATED...

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APA: Copy

Mohebi Ashtiani, Bahareh, BAGHAEI, KAVEH, HASHEMI, MEHRDAD, & Beigi, Samaneh. (2016). IMPACT OF COLON CANCER STEM CELLS ON IMMUNE RESPONSE BY PERIPHERAL BLOOD MONONUCLEAR CELLS. INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. SID. https://sid.ir/paper/935716/en

Vancouver: Copy

Mohebi Ashtiani Bahareh, BAGHAEI KAVEH, HASHEMI MEHRDAD, Beigi Samaneh. IMPACT OF COLON CANCER STEM CELLS ON IMMUNE RESPONSE BY PERIPHERAL BLOOD MONONUCLEAR CELLS. 2016. Available from: https://sid.ir/paper/935716/en

IEEE: Copy

Bahareh Mohebi Ashtiani, KAVEH BAGHAEI, MEHRDAD HASHEMI, and Samaneh Beigi, “IMPACT OF COLON CANCER STEM CELLS ON IMMUNE RESPONSE BY PERIPHERAL BLOOD MONONUCLEAR CELLS,” presented at the INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. 2016, [Online]. Available: https://sid.ir/paper/935716/en

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