THE EFFECT OF ENDOGENOUS GΑQ ACTIVATION ON EXPRESSION OF SOME β-CATENIN TARGET GENES IN SW480 CELLS

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Naraghi Leyli; MOTAMED NASRIN; A. Najafi S.Mahmoud

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Seminar Paper

Paper Information

Seminar: INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS
Year:2016 | Issue:3

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Title

THE EFFECT OF ENDOGENOUS GΑQ ACTIVATION ON EXPRESSION OF SOME β-CATENIN TARGET GENES IN SW480 CELLS

Author(s)

Naraghi Leyli | MOTAMED NASRIN | A. Najafi S.Mahmoud

Keywords

β-CATENIN

GαQ

WNT SIGNALING

COLON CANCER

Abstract

WNT SIGNAL TRANSDUCTION PATHWAYS ARE FUNDAMENTAL MECHANISMS THAT DIRECT CELL PROLIFERATION, CELL POLARITY AND CELL FATE DETERMINATION DURING EMBRYONIC DEVELOPMENT AND CELLULAR HOMEOSTASIS. THE CANONICAL WNT SIGNALING PATHWAY FUNCTIONS BY REGULATING THE PROTEIN STABILIZATION OF B-CATENIN, A TRANSCRIPTIONAL CO ACTIVATOR THAT CONTROLS THE EXPRESSION OF SOME IMPORTANT CELLULAR GENES. UPREGULATION OF B-CATENIN TRANSCRIPTIONAL ACTIVITY CAN LEAD TO NUMEROUS FORMS OF HUMAN CANCER, MOST NOTABLY HEREDITARY AND SPORADIC FORMS OF COLON CANCER...

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APA: Copy

Naraghi, Leyli, MOTAMED, NASRIN, & A. Najafi, S.Mahmoud. (2016). THE EFFECT OF ENDOGENOUS G?Q ACTIVATION ON EXPRESSION OF SOME β-CATENIN TARGET GENES IN SW480 CELLS. INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. SID. https://sid.ir/paper/936151/en

Vancouver: Copy

Naraghi Leyli, MOTAMED NASRIN, A. Najafi S.Mahmoud. THE EFFECT OF ENDOGENOUS G?Q ACTIVATION ON EXPRESSION OF SOME β-CATENIN TARGET GENES IN SW480 CELLS. 2016. Available from: https://sid.ir/paper/936151/en

IEEE: Copy

Leyli Naraghi, NASRIN MOTAMED, and S.Mahmoud A. Najafi, “THE EFFECT OF ENDOGENOUS G?Q ACTIVATION ON EXPRESSION OF SOME β-CATENIN TARGET GENES IN SW480 CELLS,” presented at the INTERNATIONAL GASTROINTESTINAL CANCER CONGRESS. 2016, [Online]. Available: https://sid.ir/paper/936151/en

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