The Effect of Concomitant Use of Grape Seed Extract Coated with Chitosan Nanoparticles and One Period of HIIT on The Rate of Cardiomyocyte Apoptosis of The Myocardial Infarction Model in Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Mohammadi Hosseinabadi Hamid; JALALI DEHKORDI KHOSRO; SHARIFI GHOLAMREZA; Mazaheri Tirani Zohreh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Sport Physiology and Management Investigations Year:2021 | Volume:13 | Issue:3 Page(s): 55-69

Download Full-Text

Persian Verion

View:

212

Download:

Cites:

Information Journal Paper

Title

The Effect of Concomitant Use of Grape Seed Extract Coated with Chitosan Nanoparticles and One Period of HIIT on The Rate of Cardiomyocyte Apoptosis of The Myocardial Infarction Model in Rats

Author(s)

Mohammadi Hosseinabadi Hamid | JALALI DEHKORDI KHOSRO | SHARIFI GHOLAMREZA | Mazaheri Tirani Zohreh | Issue Writer Certificate

Keywords

Myocardial Infarction

HIIT

Casp3

Casps9

grape seed extract

SOD

Abstract

Ischemia increases the production of reactive oxygen species and oxidative stress, which leads to cell damage directly by acting on membranes and proteins or indirectly by stimulating apoptotic pathways. One of the plants has antioxidant properties of grape seed extract that can reduce the production of free radicals. The aim of this study was to investigate the effect of concomitant use of grape seed extract coated with chitosan nanoparticles and one period of HIIT on the rate of cardiomyocyte apoptosis of the Myocardial Infarction model in rats. In this experimental study, 25 male Wistar rats who developed Myocardial Infarction by subcutaneous injection of isoprenaline(85mg/kg) were selected, Rats in this study were randomly divided into 5 groups: Control, Strok, Strok+Nano-Sup, Strok+AIT and Strok+Nano-Sup+AIT. AIT was performed with 7 intervals of each interval, including 4 minutes with intensity of 80 to 90% Vo2max and 3 minutes with intensity of 65 to 75% Vo2max. Data were analyzed using Shapiro-Wilk statistical tests, one-way analysis of variance and tokey post hoc test at α =0/05. The results showed that Casp9 and Casp3 in the myocardial induction group had a significant increase compared to the healthy control group (P = 0. 001). compared with the Myocardial Infarction group, only the stroke + exercise + grape seed group showed a significant decrease in Casp3 and Casps9 and a significant increase in SOD values (P = 0. 001). Therefore, it seems that HIIT and grape extract negatively regulate the inflammatory factor Casp3 and Casps9 of heart tissue can inhibit cardiac cell apoptosis after Myocardial Infarction and also reduce heart tissue damage.

Cites

No record.

References

No record.

Cite

APA: Copy

Mohammadi Hosseinabadi, Hamid, JALALI DEHKORDI, KHOSRO, SHARIFI, GHOLAMREZA, & Mazaheri Tirani, Zohreh. (2021). The Effect of Concomitant Use of Grape Seed Extract Coated with Chitosan Nanoparticles and One Period of HIIT on The Rate of Cardiomyocyte Apoptosis of The Myocardial Infarction Model in Rats. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, 13(3 ), 55-69. SID. https://sid.ir/paper/950329/en

Vancouver: Copy

Mohammadi Hosseinabadi Hamid, JALALI DEHKORDI KHOSRO, SHARIFI GHOLAMREZA, Mazaheri Tirani Zohreh. The Effect of Concomitant Use of Grape Seed Extract Coated with Chitosan Nanoparticles and One Period of HIIT on The Rate of Cardiomyocyte Apoptosis of The Myocardial Infarction Model in Rats. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS[Internet]. 2021;13(3 ):55-69. Available from: https://sid.ir/paper/950329/en

IEEE: Copy

Hamid Mohammadi Hosseinabadi, KHOSRO JALALI DEHKORDI, GHOLAMREZA SHARIFI, and Zohreh Mazaheri Tirani, “The Effect of Concomitant Use of Grape Seed Extract Coated with Chitosan Nanoparticles and One Period of HIIT on The Rate of Cardiomyocyte Apoptosis of The Myocardial Infarction Model in Rats,” SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, vol. 13, no. 3 , pp. 55–69, 2021, [Online]. Available: https://sid.ir/paper/950329/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops