INVESTIGATION OF RADIOIODINATION OF META-IODOBENZYLGUANIDINE COMPOUND WITH 131I ISOTOPE IN SOLID PHASE USING CU CATALYSER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DAVARPANAH M.R.; ATAR NOSRATI S.; KHOSHHOSN H.; KAZEMI BOUDANI M.; FAZLALI M.; GHANNADI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY Year:2012 | Volume:- | Issue:1 (59) Page(s): 1-7

Download Full-Text

Persian Verion

View:

555

Download:

Cites:

Information Journal Paper

Title

INVESTIGATION OF RADIOIODINATION OF META-IODOBENZYLGUANIDINE COMPOUND WITH 131I ISOTOPE IN SOLID PHASE USING CU CATALYSER

Author(s)

Keywords

META-IODOBENZYLGUANIDINEQ2

131IQ1

RADIOIODINATIONQ2

RADIOLABELLINGQ2

RADIOPHARMACETICALQ2

Abstract

In this study the radio iodination process of META-IODOBENZYLGUANIDINE with 131I isotope in presence of ammonium sulphate and Cu (II) Catalyser was investigated. In order to optimize the process, the influence of different parameters on labeling yield was studied. The results of experiments showed that the use of oil bath with temperature of 160oC is necessary. After the labeling process, purification step of the final product was carried out using Dowex-1x8 resin. The mean labeling yield was 97.2%. In this method RADIOLABELLING of MIBG with 131I (185 MBq for diagnostic dose and 3330 MBq for therapeutic dose) is quite simple and it complies with the requirements of routine production of 131I-MIBG radiopharmaceutical for diagnostic and therapeutic purposes. This paper is a narration of industrial scale production of 131I_MIBG radiopharmaceutical.

Cites

No record.

References

No record.

Cite

APA: Copy

DAVARPANAH, M.R., ATAR NOSRATI, S., KHOSHHOSN, H., KAZEMI BOUDANI, M., FAZLALI, M., & GHANNADI, M.. (2012). INVESTIGATION OF RADIOIODINATION OF META-IODOBENZYLGUANIDINE COMPOUND WITH ¹³¹I ISOTOPE IN SOLID PHASE USING CU CATALYSER. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, -(1 (59)), 1-7. SID. https://sid.ir/paper/97574/en

Vancouver: Copy

DAVARPANAH M.R., ATAR NOSRATI S., KHOSHHOSN H., KAZEMI BOUDANI M., FAZLALI M., GHANNADI M.. INVESTIGATION OF RADIOIODINATION OF META-IODOBENZYLGUANIDINE COMPOUND WITH ¹³¹I ISOTOPE IN SOLID PHASE USING CU CATALYSER. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY[Internet]. 2012;-(1 (59)):1-7. Available from: https://sid.ir/paper/97574/en

IEEE: Copy

M.R. DAVARPANAH, S. ATAR NOSRATI, H. KHOSHHOSN, M. KAZEMI BOUDANI, M. FAZLALI, and M. GHANNADI, “INVESTIGATION OF RADIOIODINATION OF META-IODOBENZYLGUANIDINE COMPOUND WITH ¹³¹I ISOTOPE IN SOLID PHASE USING CU CATALYSER,” JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, vol. -, no. 1 (59), pp. 1–7, 2012, [Online]. Available: https://sid.ir/paper/97574/en

Related Journal Papers