The effect of six weeks’,progressive resistance training on hippocampus BDNF gene expression and serum changes of TNF-α,in diabetic wistar rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Amrolahi Zohreh; Avandi Seyed mohsen; KHALEDI NEDA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sport and Exercise Physiology Year:2022 | Volume:15 | Issue:1 Page(s): 1-10

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

The effect of six weeks’,progressive resistance training on hippocampus BDNF gene expression and serum changes of TNF-α,in diabetic wistar rats

Author(s)

Amrolahi Zohreh | Avandi Seyed mohsen | KHALEDI NEDA | Issue Writer Certificate

Keywords

Diabetes

progressive resistance training

Inflammation

TNF-α

BDNF

Abstract

Purpose: Exercise is a powerful driver for reducing the complications of Diabetes. The aim of the present study was to investigate the effect of progressive resistance training on the expression of brain-derived neurotrophic factor gene in the hippocampus and serum changes of TNF α,in Wistar diabetic rats. Methods: For this study, 36 rats weighing 160 ±,10 g were randomly divided into three groups of 12 diabetic (D), diabetic and progressive resistance training (DRT) and control (C) groups. STZ solution (50 mg / kg) was used to induce Diabetes. progressive resistance training protocol three days a week, each session consisting of four to nine sets of 110cm vertical ladders with 2cm stairs and 85 °,angles of 50%, 75%, 90% with 100% maximum load capacity. Animals were dissected 48 hours after training. Samples were extracted 48 hours after GTT test. The animals were dissected and transferred to the laboratory of the Endocrine and Metabolism Research Institute to measure BDNF gene expression. BDNF gene expression was evaluated using Real Time PCR technique. Results: Results showed that resistance training increased (P = 0/001) BDNF gene expression and decreased (P = 0/002) TNF α,expression. Hippocampal weight gain was also associated with increased BDNF gene expression. Conclusion: resistance training can prevent hippocampal tissue analysis due to Diabetes and is important in diabetic patients because of the positive role of the hippocampus on memory. TNF α,expression was also decreased. Therefore, it is recommended to improve the physical health of diabetic patients.

Cites

References

No record.

Cite

APA: Copy

Amrolahi, Zohreh, Avandi, Seyed mohsen, & KHALEDI, NEDA. (2022). The effect of six weeks’,progressive resistance training on hippocampus BDNF gene expression and serum changes of TNF-α,in diabetic wistar rats. PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY, 15(1 ), 1-10. SID. https://sid.ir/paper/999813/en

Vancouver: Copy

Amrolahi Zohreh, Avandi Seyed mohsen, KHALEDI NEDA. The effect of six weeks’,progressive resistance training on hippocampus BDNF gene expression and serum changes of TNF-α,in diabetic wistar rats. PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY[Internet]. 2022;15(1 ):1-10. Available from: https://sid.ir/paper/999813/en

IEEE: Copy

Zohreh Amrolahi, Seyed mohsen Avandi, and NEDA KHALEDI, “The effect of six weeks’,progressive resistance training on hippocampus BDNF gene expression and serum changes of TNF-α,in diabetic wistar rats,” PHYSIOLOGY OF SPORT AND PHYSICAL ACTIVITY, vol. 15, no. 1 , pp. 1–10, 2022, [Online]. Available: https://sid.ir/paper/999813/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops