In order to investigate the effect of humic acid, iron and silicon nanoparticles on quantitative and qualitative yield and filling components of wheat seed under salinity conditions, a factorial layout was carried out based on a randomized complete block design with three replications in the research greenhouse of University of Mohaghegh Ardabili during 2021. Treatments included salinity levels (without salinity as a control, salinity of 35 and 70 mM by NaCl and without salinity as a control), foliar application of nanoparticles at four levels (no foliar application as a control, foliar application of 0.8 per liter of nano iron, 40 mg / l nanosilicon spraying, combined application of iron nanoparticles and silicon nanoparticles and no foliar application as a control) and humic acid spraying (spraying with water as a control and spraying 3 g/l. The results showed that combined application of humic acid and foliar application of 40 mg of iron and nanosilicon nanoparticles in the absence of salinity, increased maximum seed weight, seed filling rate, length and effective seed filling period, Spike length, 100-seed weight, plant height, number of seeds per spike, chlorophyll index (56.60, 1.183, 39, 58.45, 58.5, 39.53, 2.51, 70.6, and 57.57 respectively) and increased the yield of single plant (46.97%) compared to the conditions of non-application of humic acid and nano-oxides under the salinity of 70 mm of soil. Nanooxides (iron and silicon) can increase wheat seed yield of wheat under salinity stress conditions by improving seed filling components.