ULTRASENSITIVE DETECTION OF COCAINE BY H-SHAPE STRUCTURE OF APTAMER-COMPLIMENTARY STRANDS CONJUGATE

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MANSOURI ATENA; Taghdisi Heidarian Seyed Mohammad; Sarreshtehdar Emrani Ahmad; Mohammad Danesh Noor; ABNOUS KHALIL; RAMEZANI MOHAMMAD

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Seminar Paper

Paper Information

Seminar: GRADUATE CONFERENCE
Year:2016 | Issue:6

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Title

ULTRASENSITIVE DETECTION OF COCAINE BY H-SHAPE STRUCTURE OF APTAMER-COMPLIMENTARY STRANDS CONJUGATE

Author(s)

Keywords

APTAMER

COCAINE

GOLD ELECTRODE

H-SHAPE STRUCTURE

Abstract

INTRODUCTION: COCAINE IS ONE OF THE MOST COMMONLY ABUSED STIMULANT WHICH COULD AFFECT THE CENTRAL NERVOUS SYSTEM. THE SENSITIVE DETECTION OF COCAINE IS ESSENTIAL FOR CLINICAL DIAGNOSIS AND LAW ENFORCEMENT. APTAMERS ARE SHORT SINGLE-STRANDED OLIGONUCLEOTIDES, SELECTED BY AN IN VITRO PROCESS CALLED SELEX (SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT). APTAMERS BIND TO THEIR PRE-SELECTED TARGETS, RANGING FROM SMALL SUBSTANCES TO CELLS WITH HIGH SPECIFICITY AND AFFINITY. IN THIS WORK, AN ELECTROCHEMICAL APTASENSOR WAS DESIGNED FOR SENSITIVE AND SELECTIVE DETECTION OF COCAINE, BASED ON COMPLIMENTARY STRANDS OF APTAMER (CSS), H-SHAPE STRUCTURE OF APTAMER (APT) - CSS CONJUGATE AND GOLD ELECTRODE...

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APA: Copy

MANSOURI, ATENA, Taghdisi Heidarian, Seyed Mohammad, Sarreshtehdar Emrani, Ahmad, Mohammad Danesh, Noor, ABNOUS, KHALIL, & RAMEZANI, MOHAMMAD. (2016). ULTRASENSITIVE DETECTION OF COCAINE BY H-SHAPE STRUCTURE OF APTAMER-COMPLIMENTARY STRANDS CONJUGATE. GRADUATE CONFERENCE. SID. https://sid.ir/paper/929482/en

Vancouver: Copy

MANSOURI ATENA, Taghdisi Heidarian Seyed Mohammad, Sarreshtehdar Emrani Ahmad, Mohammad Danesh Noor, ABNOUS KHALIL, RAMEZANI MOHAMMAD. ULTRASENSITIVE DETECTION OF COCAINE BY H-SHAPE STRUCTURE OF APTAMER-COMPLIMENTARY STRANDS CONJUGATE. 2016. Available from: https://sid.ir/paper/929482/en

IEEE: Copy

ATENA MANSOURI, Seyed Mohammad Taghdisi Heidarian, Ahmad Sarreshtehdar Emrani, Noor Mohammad Danesh, KHALIL ABNOUS, and MOHAMMAD RAMEZANI, “ULTRASENSITIVE DETECTION OF COCAINE BY H-SHAPE STRUCTURE OF APTAMER-COMPLIMENTARY STRANDS CONJUGATE,” presented at the GRADUATE CONFERENCE. 2016, [Online]. Available: https://sid.ir/paper/929482/en

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