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Information Journal Paper

Title

URINE β2 MICROGLOBULIN AND OTHER BIOCHEMICAL INDICES IN β THALASSEMIA MAJOR

Pages

  443-446

Abstract

 To find if some indices have predictive value for renal complications. We conducted a cross sectional and included 80 patients with the age ranged 5-17 years, all with the proven diagnosis of b- thalassemia major. A urine and 5 ml of blood sample were obtained from all of the cases. Biochemical indices such as serum levels of creatinine, Na, Mg, Hb, and ferritin and also urine levels of Na, Mg, creatinine and b2 microglobulin was measured. All data analysis was performed using SPSS 14.0. P-Spearman test was applied to assess correlation between urine beta-2-microglobulin and other variables. Patients GFR was in normal range. Abnormal level of urine b2 microglobulin was reported in 44 patients (55%). P Spearman test proved correlation only between urine b2 microglobulin and FE-MG. We concluded that renal PROXIMAL TUBULAR dysfunction may oocur in children with b thalassemia major without clinical manifestations of renal dysfunction or decrease in GFR. We warn not to rely only on GFR as a early indicator for renal complications among children with b thalassemia major.

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    APA: Copy

    SAFAEIASL, A., MALEKNEZHAD, SH., HEYDARZADEH, ABTIN, & GHANDI, Y.. (2009). URINE β2 MICROGLOBULIN AND OTHER BIOCHEMICAL INDICES IN β THALASSEMIA MAJOR. ACTA MEDICA IRANICA, 47(6), 443-446. SID. https://sid.ir/paper/278255/en

    Vancouver: Copy

    SAFAEIASL A., MALEKNEZHAD SH., HEYDARZADEH ABTIN, GHANDI Y.. URINE β2 MICROGLOBULIN AND OTHER BIOCHEMICAL INDICES IN β THALASSEMIA MAJOR. ACTA MEDICA IRANICA[Internet]. 2009;47(6):443-446. Available from: https://sid.ir/paper/278255/en

    IEEE: Copy

    A. SAFAEIASL, SH. MALEKNEZHAD, ABTIN HEYDARZADEH, and Y. GHANDI, “URINE β2 MICROGLOBULIN AND OTHER BIOCHEMICAL INDICES IN β THALASSEMIA MAJOR,” ACTA MEDICA IRANICA, vol. 47, no. 6, pp. 443–446, 2009, [Online]. Available: https://sid.ir/paper/278255/en

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