مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

COMPARISON BETWEEN THE EFFECTS OF THE ALCHOLIC EXTRACT OF MELLISSIA OFFICINALIS AND ATORVASTATIN ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIC MALE RATS

Pages

  6-12

Abstract

 Background: Consumption of unsaturated fats reduces the serum level of lipids and leptin. THYROID hormones and leptin play pivotal roles in metabolism and their amounts are interrelated. This study was done to compare the effects of MELLISSIA OFFICINALIS extract and ATORVASTATIN on the serum levels of THYROID hormones in HYPERCHOLESTEROLEMIA rats.Materials and Methods: Consumption of unsaturated fats reduces the serum level of lipids and leptin. THYROID hormones and leptin play pivotal roles in metabolism and their amounts are inter-related. This study was done to compare the effects of MELLISSIA OFFICINALISextract and ATORVASTATIN on the serum levels of THYROID hormones in HYPERCHOLESTEROLEMIA rats.Results: The results showed that in experimental groups receiving the plant extract and ATORVASTATIN, the concentration of THYROID hormones increased, whereas the amount of the THYROID-stimulating hormone showed a significant decrease (p<0.05).Conclusion: MELLISSIA OFFICINALIS extract decreases TSH but it increases T3 and T4. Further studies are required for applying this extract to the treatment of hyperthyroidism.

Cites

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    • Cite

    APA: Copy

    ZAREI, ALI, CHANGIZI ASHTIYANI, SAEED, SOKHANDANI, MANSOUR, REZAEI, AZAM, ZAHEIRI, SAEED, & TAHERI, SOHEILA. (2013). COMPARISON BETWEEN THE EFFECTS OF THE ALCHOLIC EXTRACT OF MELLISSIA OFFICINALIS AND ATORVASTATIN ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIC MALE RATS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 15(8), 6-12. SID. https://sid.ir/paper/609378/en

    Vancouver: Copy

    ZAREI ALI, CHANGIZI ASHTIYANI SAEED, SOKHANDANI MANSOUR, REZAEI AZAM, ZAHEIRI SAEED, TAHERI SOHEILA. COMPARISON BETWEEN THE EFFECTS OF THE ALCHOLIC EXTRACT OF MELLISSIA OFFICINALIS AND ATORVASTATIN ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIC MALE RATS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2013;15(8):6-12. Available from: https://sid.ir/paper/609378/en

    IEEE: Copy

    ALI ZAREI, SAEED CHANGIZI ASHTIYANI, MANSOUR SOKHANDANI, AZAM REZAEI, SAEED ZAHEIRI, and SOHEILA TAHERI, “COMPARISON BETWEEN THE EFFECTS OF THE ALCHOLIC EXTRACT OF MELLISSIA OFFICINALIS AND ATORVASTATIN ON SERUM LEVELS OF THYROID HORMONES IN HYPERCHOLESTEROLEMIC MALE RATS,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 15, no. 8, pp. 6–12, 2013, [Online]. Available: https://sid.ir/paper/609378/en

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