Background: Metabolic Syndrome (MetS) is a physiological and biochemical disorder that are associated diabetes or elevated fasting blood sugar, obesity, triglyceride level and cholesterol disorders and hypertension.. The syndrome has been given several names such as Insulin resistance syndrome, Plurimetabolic syndrome, Reavens syndrome, Syndrome X and the deadly quartet. Some recent evidence have shown a significant correlation between MetS and lung disease especially Chronic Obstructive Pulmonary Disease (COPD). So we aimed to estimate frequency of MetS among a sample of Iranian patients of COPD (Chronic Obstructive Pulmonary Disease) and Chronic Bronchitis (CB).Methods: In this cross-sectional study, 204 COPD and CB Known cases evaluated as MetS development and demographic criteria, lipid profile, C reactive Protein (CRP) blood level, and smoking history and correlation of these criteria were assessed in these patients.Results: Frequency of MetS involvement among these subjects was approximately 48%. Age (p=0.003), abdominal obesity (p<0.001), high TG amount (p<0.001) and positive CRP (p=0.04) were correlated with MetS involvement.Conclusions: MetS was more frequent among COPD and CB patient.Age and underlying systematic inflammation Appears to be related to MetS.