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مرکز اطلاعات علمی SID1
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
Title: 
Author(s): 

Issue Info: 
  • Year: 

    0
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    -
Measures: 
  • Citations: 

    11
  • Views: 

    885
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title: 
Author(s): 

Issue Info: 
  • Year: 

    0
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    -
Measures: 
  • Citations: 

    22
  • Views: 

    1330
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 1330

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    1-9
Measures: 
  • Citations: 

    0
  • Views: 

    1446
  • Downloads: 

    629
Abstract: 

Background: According to some studies, fetal wound in contrast with adult wound heals without scar formation which is probably due to amniotic fluid around the fetus, unique extracellular matrix and the fetal immature immunity. It is supposed that biochemical and physical characteristics of amniotic fluid prepares the conditions for wound healing without scar formation. The goal of this study was to compare the scar diameter of uncomplicated appendectomy by Rocky-Davis incision with scar diameter of cesarean section by Pfanneistiel incision in order to evaluate the effect of amniotic fluid on scar diameter.Methods: In this analytic within-patient study all women with uncomplicated appendectomy by Rocky-Davis incision who were pregnant or had history of cesarean in the last 18 months were included (2007-2009). After 18 months of operation (appendectomy and cesarean), scar diameters were measured in three points (first, middle and end of scar) and the mean was calculated. Then the mean scar diameter of appendectomy was compared with the mean scar diameter of cesarean in each patient. For data analysis we used T-test, Paired T-test, correlation coefficient and regression tests.Results: In this study the effect of weight and height on scar diameter was evaluated. Mean scar diameter of appendectomy was 2.09±0.677 millimeter and the mean scar diameter of cesarean was 0.467±0.633 millimeter which was significantly less than appendectomy scar diameter (p=0.008).Conclusion: It seems that the presence of amniotic fluid in the first hours of healing decreases the future scar diameter.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 1446

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    10-19
Measures: 
  • Citations: 

    0
  • Views: 

    1506
  • Downloads: 

    265
Abstract: 

Background: Several endocrine and locally acting factors are involved in the complex process of ovarian follicle growth and oocyte maturation. In vitro follicular culture systems, at various developmental stages, allow the identification of these factors and the understanding of their mechanisms of action. Keeping in mind the significance of the influence of environmental factors on the follicle growth, this work focuses on the effect of some endocrine and paracrine factors on the growth and differentiation of preantral follicles during the in vitro follicular culture using the rodent (mouse) model.Methods: Our study was semi-experimental. First task of the study was to choose an appropriate serum type. Prepubertal gilt serum, embryonic stem cell tested fetal calf serum, hypo gonadal mouse serum and fetal calf serum were tested during the present study. Effect of the culture period was also evaluated on the follicle growth. After carefully selecting the optimum growth conditions, the effect of FSH was evaluated on the growth and viability of the follicular and oocyte maturation. Different concentrations of FSH (5, 20, 40, 60, 100, 140, 180 and 220 mIU/l) were added to the culture medium (containing 25-30 follicles each) during separate experiments.Results: After experiments, fetal calf serum (FCS) was chosen for the evaluation of the effect of FSH. During the present experiment, 100 mIU/ml FSH showed highly significant effect on the follicle and oocyte growth. Follicle survival rate also increased (91%) as compared to that grown without this gonadotropin (28%). Oocyte maturation (61%) and germinal vesicle breakdown rates (81%) also showed an increase (p£0.05).Conclusion: These results have suggested that the exposure to FSH and FCS before the formation of antrum had a positive effect on the follicle survival and oocyte robustness.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    20-26
Measures: 
  • Citations: 

    1
  • Views: 

    892
  • Downloads: 

    236
Abstract: 

Background: Candidiasis is one of the most common fungal infections in oral cavity. About 85% of this infection is caused by Candida albicans a flora of mouth. Since one of the problems in denture users is it's contamination with C.albicans and discoloration, and lack of information about adhesion of C.albicans to different resins, we designed this study to compare the effect of two types of acrylic resin on adhesion of C.albicans.Methods: This was an experimental study within that 36 samples from Bayer and Acropars acrylic resin were added in tubes containing suspension of 1×106 (CFU/ml ) of C.albicans. Then tubes were incubated at 37oc for 40 and 120 minutes. After incubation, the samples were transferred in 1ml of sterile saline and after resuspension by shaking a known quantity of each was inoculated on sabouraud dextrose agar and incubated at 37οc for 48 hours and after that, formed colonies were counted and were analyzed by Mann-u- Whitney test.Results: These two acrylic resins did not reveal statistical significant differences in two 40οc and 120οc different lengths of the time from the point of adhesion. Also Bayer acrylic resin did not show any significant differences from the point of adhesion in to different lengths of times. But dissimilarly was significant for Acropars acrylic resin which indicated adhesion with the passage of the time. (p<0.1)Conclusion: These two Acrylic resins do not have any priority to each other from the view point of non-adhesion to Candida albicans, but Bayer acryl is more appropriate particularly for those who are with weak hygiene and are more susceptible to fungal infections. Surface roughness of acrylic resins and their components, characteristic and surface factors have essential role in adhesion of C.albicans.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 892

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    27-33
Measures: 
  • Citations: 

    5
  • Views: 

    2822
  • Downloads: 

    992
Abstract: 

Background: Breast cancer is the most common cancer among women especially in eastern Mediterean region. Disease-free survival is common to evaluate the treatment of cancers. Several factors have been determined as prognostic factors for disease-free survival in studies.Methods: In this cross-sectional study, during 2005-2007, 153 women with breast cancer were treated in Fayazbakhsh hospital, Tehran. These patients had no metastasis at the time of diagnosis. Patients underwent MRM or BCS surgery. All patients followed until 2011 April. Metastases were diagnosed with x-ray, Biochemical methods, ultrasound with oncologist confirmation. A Cox's regression with time to first event variable was used to determine the prognostic factors. Kaplan-Myer method was used to estimate the survival function. All statistical methods ran in R software version 2.10.Results: Out of 133 patients, 25 (18.8%) died and 108 (81.2%) were alive. Out of alive patients, 99 (74.4%) without metastasis and 9 patients (6.8%) experienced a metastasis. Using Kaplan-Myer estimation showed that disease-free survival was 64 months, and five years rate of disease-free was 72 percent. Increasing in disease-free survival was associated with low grade of tumor, low number of involved lymph nodes, ER negative and HER2 negative. Odds ratio of metastasis or death for HER2 positive was 2.46 times of HER2 negative. Patients with grade 3 had risk of metastasis 1.69-fold of grade2. Conclusion: The result of this study showed that HER2, ER, Grade and number of involved lymph nodes were prognostic factors. Age, size of tumor and PR were not identified as prognostic factors.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 2822

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    34-45
Measures: 
  • Citations: 

    2
  • Views: 

    1347
  • Downloads: 

    704
Abstract: 

Background: The global burden of cancer continues to increase largely because of the aging and growth of the world population alongside an increasing adoption of cancer-causing behaviors, particularly smoking and various environmental factors. A variety of cancers data in special geographic areas can help define medical programs for treatment and screening of high-risk groups. Since cancer types has not been reported within districts and neighbourhoods of Tehran city so far, this study could be considered as the first in this respect, which defines cancer epidemiology in the catchment area, and on the other hand, paves the provision of equitable services patient who need these facilities.Methods: This is the cross sectional study that shows cancer distribution patern. Incident cases from Tehran residents covered by the Iran University of Medical Sciences were obtained, which included almost 55% of the total cancer incidence in Tehran in 2007. Districts covered by the university were located in west and southwest of Tehran including districts 2,5,6,9,18,21, and 22 cases of other districts refered to Iran university that identified incidence cancer but results must interpreted with caution since those resident districts have not been covered population data were obtained from the previous census in 2006. Age and sex standard rate were calculated based on Iranian standard population. Cancers distribution maps were developed using available addresses, indicating districts and neighbourhoods in GIS. Common cancers difference within covered districts was tested by Fisher exact test.Results: Cancer incidence in specified districts of Tehran was 72.822 in 100000 population, where district 6 had the highest incidence (ASR=90.552) followed by district 2 (ASR=71.503) and the least incidence was in district 18 (ASR=34.991). This difference was significant within districts by Fisher exact test. The highest ASRs in women was 87.517 in districts 6 and 2 (71.621) and in male respectively 94.683 and 70.919. Highest incidence within neighbourhoods were Abasabad, Qaemmaqam and Gand in males and Ddaneshgah, Arjantin and Shiraz in females. High cancers ASR consisted of breast (9.018), colorectal (4.94), prostate (4.174), stomach (3.711) and skin (3.522).Conclusion: More cancer aggregation, which was observed in districts 2 and 6 within the university catchment area and districts 1 and 3 out of this territory, warrants more researches to investigate what factors in the specified districts and neighbourhoods has led to this condition.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 1347

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Issue Info: 
  • Year: 

    2011
  • Volume: 

    18
  • Issue: 

    89
  • Pages: 

    46-53
Measures: 
  • Citations: 

    0
  • Views: 

    998
  • Downloads: 

    339
Abstract: 

Background: Dermatophytosis is common cutaneous fungal disease with worldwide distribution. Interleukin8 (IL-8) realized from keratinocytes in the presence of dermatophytic antigens causes induction of acute responses in dermatophyte infection and subsequently production of acute phase proteins occurs in hepatocytes. C-reactive protein (CRP) and Mannose-binding lectin (MBL) are acute phase proteins. Since few researches in the case of acute phase proteins in dermatophytic infections has been accomplished, this study has been designed for determining serum CRP and MBL levels in patients affected to dermatophytosis.Methods: This was a cross sectional study and samples were carried out on 96 healthy individuals and 105 patients affected to dermatophytosis with non probable and in access procedure. For isolation and identification of dermatophyte direct microscopic examination, culturing and complementary examinations were done and for determination of serum CRP and MBL levels in healthy individuals and in patients ELISA test were used. For investigation of relevance between variables, Chi-square, Fisher exact, Mann-Whitney and Roc curve analysis were used and p< 0.05 was considered as meaningful level.Results: The median serum CRP level in healthy individuals and in patients group was 3.31±3.32 mg/ml and 16.60±35.96 mg/ml (p<0.001) respectively and the median serum MBL level was 1.53±1.87 mg/ml and 1.97±2.03 mg/ml (p=0.039) respectively. CRP (p<0.001) and MBL (p=0.042) were determined meaningful parameters for dermatophytosis. MBL deficiency (MBL concentrations <1 mg/ml) was higher in control subjects (56.2%) than in patients (41.0%). Conclusion: Findings of this study indicate increased concentrations of CRP and MBL in patients affected to dermatophytosis and their role in this infection. Probably observation of high frequency of MBL deficiency in healthy individuals in compare with patients group indicates that it is not predisposing factor in affecting to dermatophytosis.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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