In order to study the effects of sulfur and compost on increasing nutrients availability of soil, nutrients uptake by wheat, and grain yield, an experiment with was conducted with 3 treatments and 4 replicates, using a complete randomized block design .The experiment was carried out at Gachsaran research station on a soil that was highly calcareous. The three treatments consisted of a control, sulfur application (300 kg/ha), and sulfur (300 kg/ha) + compost (20 ton/ha). Although yield differences were not significant, compared with the control treatment, grain yield increased by 190 kg/ha (3.6%) and 330 kg/ha (8.4%) for, respectively, sulfur and sulfur + compost supplements. Also, the concentration of P, K, Fe, Zn, and Cu in the seeds increased by 5.5,11, 39, 5, and 29% with sulfur supplement, compared with the control. Mn-concentration did not change. At the same time, the increase in the absorption of P, K , Fe, Mn, Zn, and Cu by the seeds were, respectively, 78, 73, 68, 42, 64 and 54 % with sulfur + compost supplements, compared with the control. Results also showed that in the sulfur treatment, the available Mn and K of the soil increased after harvest by 121 and 7%, respectively, but no effect was observed on the concentration of other nutrients. However, sulfur +compost treatment increased avail. P(87%), K(34.5 %), Fe (130%), Zn (490%), and Cu (>100%), compared with the control. But, the amount of increase in avail. Mn was only 63%, which is lower than the 121% increase obtained in the former treatment.