The aim of this research was to investigate the correlation between knowledge management and organization climate in different institutions of Higher Education. The research method is descriptive and of correlational type. The population included the staff, faculty members and employees, of different institutions of higher education in Iran, such as IAU, Payam-e-Noor, and Elmi-Karbordi. Based on Morgan chart, our sample included 165 people, which were selected through stratified random sampling. To collect the data, two standardized questionnaires were used. The first one was knowledge management questionnaire with 38 five-choice questions including such items as, knowledge acquisition, knowledge sharing, and knowledge use. The second questionnaire measured the organizational climate with 42 questions, 21 of which were related to managers' behaviors towards the staff and the other 21 were related to staff behaviors towards each other. To analyze the data, both descriptive and inferential statistics were used through the application of SPSS. Data analysis revealed that there was a positive correlation between knowledge management and organizational climate in different institutions of Higher Education. It also showed that increasing the knowledge of employees in different institutions of higher education could improve organizational climate in such institutions.