Germination is a crucial stage in seedling establishment and hence plays a key role in crop production. Crop establishment but, depends on the interaction between environmental stress and seed quality. This experiment was conducted to evaluate the reaction of aged cottonseed in various levels of salinity and germination of cotton seed. The research was carried out in factorial design with CRD arrangement in three replications. Treatments included salinity in 6 levels (0, 5.5, 11, 16.5, 22 and 28 ds m-1) and 7 seed aging times (0, 12, 24, 48, 72, 96 and 120 hours accelerated aging periods). Results indicated that the rate and percentage of seed germination and dry weight of seedling reduced significantly with increasing the levels of aging and salinity. Also, the interaction between salinity and seed aging was significant. In all aging times, germination percentage, germination rate also seedling dry weight reduced when salinity increased but rate of decreasing was more in seeds which had high aging intensity. As a result, in 120 h aging treatment, no seed was germinated in 28 ds m-1 salinity, but in this salinity level, the germination of control seeds (not aged) was between 18%-65%. Generally, results of this study showed that tolerance of cotton seeds to salinity decreased with increasing aging period, then in saline regions, for obtaining optimum density and maximum yield, must avoid of sowing aged seeds.