In recent years, remote sensing technology has provided valuable information in the field of mineral exploration. Satellite data have been used widely in geology and exploration and to determine the location of mineral deposits. The remote sensing techniques, has been used significantly in the updating of geological maps, improved quality, and thematic mapping such as alteration zones maps, rock units, lineaments and fracture patterns, and has saved time and cost of in mineral potential mapping. This project was conducted in the Espeed iron ore deposit area with 13.87 km2 which is located in 60 km from the West Qom city, Iran. Studied area, in general, is composed of volcanic zones (mainly quartz andesitic- andesitic masses with volcanic ashes and pyroclastic materials, with some outcrops of acidic tuff dykes) and Tertiary sedimentary rocks. Mineralization occurred in the surface of quartz andesitic rock as disseminated of hematite and specularite mineralization. In Preliminary exploration operations conducted in this ore deposit, some trenches were dug in the altered zones associated with the faults that two trenches have been determined hematitic zone with 65-75% Fe2O3. After the stripping operation, has revealed a considerable extent of iron mineralization in the form of hematite. In this project, ASTER satellite images were used in different band combinations and LS-Fit (Linear Band Prediction), Matched Filtering, SAM (Spectral Angle Mapper) and band combination method for extraction iron oxide alteration zones. According to the results of field survey and the availability of an iron alteration zone-as an indicator- in the area, were provided an opportunity for assessing the accuracy, control and compare the results of remote sensing studies using these methods with field studies. Finally, among the investigated methods, 4.3.1 band combination method, was a most harmonious result with field studies to identify iron alteration zones in this exploration area.