Journal of Kermanshah University of Medical Sciences
Year:2002 | Volume:6 | Issue:3|Papers Count:11

Introduction and Objectives: Since cyanide is a strong inhibitor of cytochrome oxidase and metabolism, we need to know whether it is useful in increasing cardiac resistance to ischemia.Materials and Methods: Male rats received either 1.7mg/kg potassium cyanide or normal saline transperitoneally for 35 days. Then, isolated hearts were examined at baseline, during ischemia and after return to normal perfusion state.Results: Coronary blood flow, left ventricular pressure and contractility (dp/dt) were similar in two groups, but at ischemic state (p<0.005) and at recovery to normal state (p<0.05) there were statistically significant differences in left ventricular pressure and contractility (dp/dt) between the two groups.Discussion and Conclusions: It seams that cyanide induce cardiac resistance to ischemic effects in rats.

Introduction and Objectives: This study was done to compare the effectiveness of Fluconazole and Clotrimazole in treatment of candida albicans vaginitis in patients referring to health centers affiliated with Shahid Beheshti University, during the year 1379.Materials and Methods: 70 patients received either a single oral dose of 150 mg Fluconazole (35 patients) or 7 days course of vaginal Clotrimazole. Clinical history, smear, and culture were obtained.Results: Positive Clinical and laboratory response was seen in 77% and 74% and 91% and 77% of Fluconazole and Clotrimazole groups, respectively. There were no statistically significant differences between the 2 groups regarding clinical or laboratory responses to treatment.Discussion and Conclusions: If confirmed by others, a single oral dose of 150 mg Fluconazole should replace the 7 days course of vaginal Clotrimazole.

Introduction and Objectives: There is some controversy over the clinical efficacy of Hydroxy urea in Thalassemia intermedia.Materials and Methods: Therapeutic efficacy of Hydroxy urea was evaluated in 16 patients with thalassemia intermedia, by measuring total hemoglobin and hemoglobin F levels before and 6months after treatment with Hydroxy urea (20 mg/kg/day). Results: Mean increases in total hemoglobin and hemoglobin F levels 6mo after treatment with Hydroxy urea were 1.47±1.12 gm/dl and 1.43±1.12 gm/dl, respectively. The most common mutation was found to be IV S II-I betaglobin.Discussion and Conclusions: Use of Hydroxy urea in thalassemia intermedia is associated with increases in total hemoglobin and hemoglobin F levels.

Introduction and Objectives: this study was done to assess the effects of physical exercise on sleep of hospitalized orthopedic patients in cast and having traction, in selected centers in Tehran, during the years 1374-75.Materials and Methods: The study participants were 40 hospitalized males 20-60 years old. Results: 80% of patients had difficulty falling asleep, 75% experienced frequent awakening, and 52.5% awakened early. Physical exercise was associated with sleep improvement in all patients (p<0.001). Discussion and Conclusions: Physical exercise should be promoted in hospitalized patients in order to improve their sleep.

Introduction and Objectives: This descriptive study was done to determine the Anthropometric measures of women of reproductive age in Mashhad during the years 1376-1377.Materials and Methods: 2000 women aged 15-49 years, were recruited from housewives, employees, and students. Weight, height, circumference of mid upper arm, calf and wrist, and triceps skin fold were measured.Results: Mean ± SD values are : weight:58.2± 23.9 kg , height:156.5± 6.1 cm , body mass index:23.6± 4.4kg/m2 , ideal weight:103.5 ± 15.9%, mid upper arm circumference:26.6 ± 9.3 cm, calf circumference:33.7± 3.42 cm, triceps skin fold 16 ± 6.4mm. Highest mean height and lowest mean weight were seen in 15-19 and 20-24 years groups, respectively. Highest mean weight and lowest mean height were seen in 40-45 years group.Discussion and Conclusions: Low anthropometric measures are indicative of poor nutrition among the 2 extremes of reproductive age groups. We suggest that national reference values for anthropometric measures be determined.

Introduction and Objectives: This study was done to evaluate the level of noise pollution due to traffic in Kermanshah.Materials and Methods: In the first step of this cross sectional study, general noise was measured in midpoint between street and sidewalk, using Quest-2900 and B&K 2230, at 4-8 pm at 328 points in main streets of Kermanshah, at spring of 1379. In the second step, the level of noise received by residents (shopkeepers and police) was measured according to Leq factor, using Quest dosimeter.Results: Background noise was very high. L50 and L90 were 68 and 63 dB, respectively. Shopkeepers received 74.3 and 75.6 dB, at squares and streets respectively, and police received 73.5 and 75dB, at squares and streets respectively.Discussion and Conclusions: Noise pollution due to traffic in Kermanshah is much higher than standards. Broadening the streets and placing noise absorbent panels in streets is recommended.

Introduction and Objectives: This is a descriptive report of vascular trauma cases in Tehrans Taleghani Hospital.Materials and Methods: The files of vascular trauma cases during the years 1997-2000 were evaluated.Results: 157 patients presented with vascular trauma. Mean age was 28.5 years, with a male to female ratio of 7 to 1. 63% of injuries were penetrating and 56% were in lower extremities. 18% sustained iatrogenic trauma and 11% had trauma during iv drug abuse. 15 cases had bone fractures.715 had pulse deficits, 33% sensory deficits, 30% motor deficits, and 14% nerve transection. Interpositional graft was used in 77 cases, and the rest were treated with patch angioplasty, primary closure and ligation. 8 cases died postoperatively and 13 cases underwent amputations; Nevertheless, and despite the fact that we had not evaluated the patients with angiography or Doppler sonography postoperatively, we regard the results "successful" in 86%.Discussion and Conclusions: High rates of Iatrogenic trauma and trauma following iv drug abuse needs "special evaluations". A program of continuous medical education about vascular trauma is suggested.

Introduction: We are reporting a case of familial dysautonomia presenting with bilateral corneal ulcer.Case report: A 1-year old boy presented with red eye and bilateral corneal ulcer. Diagnosis of familial dysautonomia was made based on "clinical and laboratory data." Conjunctival flap and lateral permanent tarsorrhaphy was done.Discussion and Conclusions: Local Ophthalmologists and pediatricians should be aware of this presentation of familial dysautonomia.