Jentashapir Journal of Cellular and Molecular Biology
Year:2013 | Volume:4 | Issue:2|Papers Count:12

Background: Parents’ mental health could be intensively influenced by disabled child, especially when there is a disorder such as autism including a wide range of behaviors and particularly social behaviors. This study aimed to evaluate the effect of negative mood management training on mental health and depression of mothers of Children with Autistic disorder.Method: Sample of this study consists of thirteen mothers of children with autistic disorder. Pre test consist of demographic questionnaire, General Health Questionnaire (GHQ) and Beck Depression Inventory (BDI), the post-tests were completed after 4 sessions of the workshop.Result: the result of repeated measures and paired samples t-test analysis showed that the workshop improved mothers’ mental health in subscales of anxiety/insomnia, physical symptoms, and social function (p<0.05). There was no significant change in mothers’ depression and total scores of mental health.Conclusion: The results showed that negative mood management training could be included as an effective part of mental health improving interventions for mothers of children with autistic disorder.

Background: Broccoli with scientific name, Brassica Oleracea, from Crucifera genus is a vegetable full of vitamins (such as A, C and E), fibers, Beta-carotene, calcium, iron, zinc, selenium and Flavonoids, which is a strong antioxidant and it can prevent from damages of Reactive Oxygen Species in body The present study investigated the effects of Brassica Oleracea extract on LH, FSH and Testestrone hormones levels.Methods: Forty adult male wistar rats were used. They were feeded from standard Pellets. The animals were divided into five groups: Control, Blank, Experimental 1, Experimental 2, and Experimental 3 (n=8). The plant extract doses used for experimental groups 1, 2, and 3 were 0.5gr/kg, 1gr/kg, and 2gr/kg respectively. Using gavage the hydro-alcoholic extract was orally administered to animals. After 28 days of feeding, the animals were made unconscious by ether, and blood samples were obtained from the heart. Then all groups’ blood serums were separated, and concentrations of LH, FSH and testosterone hormones were evaluated using Elisa Method.Results: In all groups, the levels of LH hormone had not significant increase, but the increased amount of Group 2 was more than the others; the levels of FSH had a significant decrease in the Experimental Group 3 as compared to Control Group. Concentration of testosterone in the Experimental Group 2 showed a significant increase as compared to Control Group.Conclusion: Findings showed that the effect of Brassica Oleracea extract was mostly presumed due to existence of flavonoids which results in increasing and decreasing of hormones, Flavonoids have a phytoestrogen structure that can be used in steroid synthetic cycle [in the other hand, they can be treated as a antioxidant which could eliminate ROSs in body].The investigation revealed that Brassica Oleracea hydroalcoholic extract has a dose-dependent activity. The obtained suitable dose in the study was 1gr/kg.

Background: Drop-out (discontinuing treatment after the first visit) is one of the main causes of failure in obesity treatment. The aim of this study was to investigate the pattern of drop-out in overweight or obese outpatients in Ahvaz, Iran.Methods: A total of 575 overweight or obese individuals (female: 469, male: 106) aged 18– 65 attending an outpatient dietician office for the obesity treatment were investigated. Variables such as age, gender, marital status, Body Mass Index (BMI), educational level, job, self body image, and some eating behaviors were evaluated. Relationships between these factors and drop-out rate were tested by chi-square and logistic regression tests.Results: Drop-out rate was 56.3% (79.3% in females and 20.7% in males). The non continuer patients had less negative image about their body weight (P=0.006) as considered themselves in normal weight range. Drop-out rate in employed participants were higher and most of continuers were jobless or housewives (P=0.022). The results showed that from point of view of body fat percentage there was a statistically significant difference between two groups (P=0.007).The self body image was the only significant predicting variable of drop out in multiple logistic regression test.Conclusion: Findings revealed that overweight or obese individuals with incorrect body image are at higher risk of treatment drop-out.

Background: This study investigated the anti-inflammatory effect of Fumaria Parviflora due to its Fumaric acid, flavonoid and phenolic compounds for skin diseases, relieves itching and eczema.Methods: Male wistar rats (ranging 150-180g in weight) were used. For preparation of the hydro alcoholic extract, Plant powdered were macerated in ethanol 70%, then extract were concentrated for further use. Five treatment Animal groups received dose of 200, 400, 600, 800 or 1000 mg/kg of Fumaria Parviflora extract, Positive control group received a dose of 300 mg/kg aspirin and negative control group received serum physiology solution with dose of 5 ml/kg via intra-peritoneal injection of traits. After half an hour, 100 micro liters of carageenan 1%was subcutaneously injected into the rat’s paw and then the volume of the rat’s paws were evaluated using PLethysmometer apparatus. once every hours between the first and fifth hours Results: 200 and 400 mg/kg doses of extract had less effect on decreasing the paw’s edema in comparison with animal group received aspirin (p<0.05). However, dose of 600, 800 and 1000 mg/kg of the extract had more effects on decreasing the paw’s edema, but difference between two groups is not statistically significant (p>0.05).Conclusion: Fumaria parviflora hydro alcoholic extracts with doses of 600, 800 and 1000 mg/kg and aspirin (300 mg/kg) significantly decreased the paw’s edema in the subject field rats compared to group received 5ml/kg of Serum physiology solution. Moreover, as the fewer side effects are to be expected for lower dose of 800 mg/kg; the most appropriated dose was selected for this extract. Using complimentary examinations in toxicity of this extract it could be used to decrease the inordinate intake of NSAIDs.

Background and aim: There is inconclusive evidence about the relationship between toothbrush wear and plaque removel. The aim of this study was to compare the effectiveness of new and 3 monthold toothbrush in the removal of dental plaque.Materials and methods: In a randomized single blind clinical trial 63 students attended from Awaz Dental School. Subjects were divided to three groups. Plaque was scored pre-brushing and post brushing new toothbrushes using the Turesky et al index. After 3 months, plaque was rescored pre-brushing and post-brushing 3-month–old brushes following 48h periods of no oral hygiene. Collected data analyzed using Paired-t-test and ANOVA.Results: All 60 subjects compelated this study. Both the new and 3-month-old brushes reduced plaque scores significantly than prebrushing time. The percentage reductions in plaque scores achieved with the new brushes were not significantly different from those achieved with 3-month-old brushes from total surfaces. Compared with 3 type toothbrushes, no significant different were found for plaque score reduction with the new and 3-month-old brushes.Conclusion: This study found that 3-month-old toothbrushes were as effective as new brushes when used 3 brands toothbrush to removal of dental plaque.

Background: Nowadays, work related stress appears to affect almost all people with connected clinical works. The purpose of this research was to study the relationships of work stress and work engagement with the satisfaction from lives of nurses in Ahvaz governmental hospitals.Methods: A correlation study was carried out. Nurses from governmental hospitals were selected and statistical sample universe was developed. From this universe, a total of 128 nurses were selected by multistage random sampling method. Work Engagement Scale, Satisfaction with Life, and Nursing Stress questionnaires were used to collect the required data. Descriptive and inferential statistical methods (simple correlation and regression) and SPSS software were used for data analysis.Results: The results showed that there were significant correlations between work engagement and work stress with life satisfaction. All subscales of Work Engagement Scale had significant positive correlation with the nurses’ life satisfaction. Among nursing stress subscales, the variables of inadequate emotional preparation and patients' death didn’t have any significant correlation with satisfaction from life. The other subscales had negative correlation with life satisfaction. Regression analysis results that the dedication to patients' variables were able to predict %31 of variance of life satisfaction.Conclusion: In order to increase the satisfaction with life and stability of family measures, work stress and work engagement of nurses should be considered.

Background: Superoxide dismutase is an important mammalian antioxidant that is found in all tissues and its role in periodontal disease is emphasized. Chronic periodontitis is the most common form of periodontal disease that causes destruction of connective tissue and bone around the teeth. One way to help the treatment of periodontal disease is use of oral supplements such as chlorhexidine, which has an inhibitory effect on free radical products. This study aimed to evaluate effect of chlorhexidine (0.2%) mouthwash on salivary superoxide dismutase activity of referred patients with generalized moderate chronic periodontitis from Ahvaz Dental School.Methods: A total of 30 cases were included in this study; 15 patients with and 15 people with no any symptoms of periodontitis equally. Control and case groups were allocated and two samples of saliva were collected before and after apply of chlorhexidine mouthwash.SOD levels were determined by ELISA method. Using T-Test methods, the collected data were analyzed.Results: The findings showed that the superoxide dismutase activity in the control group before use mouthwash was more than the case group and there was statistically a significant difference between two groups (P=0.044). After eliminating chlorhexidine mouthwash, superoxide dismutase activity in either groups has increased but difference was not statistically significant (P>0.05).Conclusion: The results conveyed that SOD activity was reduced in periodontal patients and for that reason, the use of chlorhexidine mouthwash could change the SOD activity.

Introduction: One of the main job problems, which usually can be seen pressures of job among human organizational service workers, is burnout phenomenon. The purpose of this study was to determine the perceived levels of relationship between burnout and the public health for teacher working in Abadan high schools.Methods: this is a descriptive cross - sectional study that sampling method was conducted using Size Cluster system. The A total of 120 teachers working in Abadan high schools male (n=37) female (n=83) Comprised this study groups for the current investigation. Data were collected from three demographic questionnaires and the Maslach Burnout Inventory General Health Goldberg was formed. Data analysis was done using SPSS-17 software.Results: In this study, 69.2% female, 95 % married, and 81.7 % had a bachelor's degree. The results showed that burnout scores in the areas of emotional exhaustion 8.91±6.75, depersonalization 2.56±9.07 and the personal success of 37.35±9.57 and the mean score of General Health of teachers 16.42±8.25 respectively. Between gender (P<0.01) and marital status (P<0.05) there was a significant association of depersonalization. Between age and emotional exhaustion (P<0.01) and depersonalization (P<0.05) was correlated to general health, but the results showed that there is no significant relationship between general health of teachers with the variables such as: age, sex and marital status.Conclusion: Finding from this investigation revealed that burnout is a common problem among teacher working in Abadan high schools. From point of view of the public health and teachers’ demographic characters the results could not find any significant relationship. Since teachers are the messenger of education, therefore, their health is very important. Because if the teacher is not healthy, cannot be a good breeder for students who are society's future. Therefore recommended education department in the field of public health should be fun promotion programs for families with more effort.

Background: Sweet's syndrome which is characterized by fever and acute onset of skin lesions is in many times associated with other conditions including renal disease. Type of association and true rate is not yet clear.Case report: We report a woman with end stage renal disease and peritonitis who developed Sweet's syndrome.Conclusion: Sweet's syndrome can be associated with renal diseases, yet true association is not established. Case reports can add to field and increase data on this issue.