Objective(s): To determine the relationship between blood groups & Rh factor with rate of infection to cholera in Barn.
Material & Methods: Relationship between cholera and blood groups in 74 patients, who were clinically and para-clinically proved to be infected with Ogawa during the cholera epidemic in 1997, was determined. A total of 74 healthy individuals with similar socio-economical, sex and age were selected as controls.
Results: The mean age of male and female was 11.3±4.7 and 14.5±5.2 year, respectively. Prevalence of blood groups for A, B, O and AB in patient group was 14.9,21.6,62.6 and 1.3 percent, respectively, while it was 32.4, 33.7, 29.7 and 4.2 percent in control group. The result showed that the blood group O was the highest risk groups among the others (Odds ratio = 3.8, 95% CI=1.85 - 8.19). Also this investigation showed that individuals with Rh-were 2.3 times more susceptible to disease than those with Rh+ (Odds ratio = 2.3, 95% CI= 0.78 - 6.61).
Conclusion: It is recommended that any prophylactic measures should be directed against those more than 10 years of age with blood group O in endemic and epidemic areas.