Aim: The purpose of this study was to determine and identify the effect of psychodrama on neuropsychological functions of male elementary school students in Salas Babajani earthquake-stricken city. Methods: This study was quasi-experimental, a pre-test/ post-test with a control group. The statistical population of the present study was all-male elementary school students with post-traumatic stress disorder in Salas Babajani city, where four schools were selected. 40 individuals who were selected by purposive sampling method and were randomly divided into two equal groups: experimental group(20 individuals) and control group(20 individuals). The experimental group treated 13 90-minute sessions according to psychodrama therapy(based on Moreno's view) and then the post-test was performed for both groups. The research tools were diagnostic interviews according to DSM-5 criteria to determine post-traumatic stress disorder, a PTSD Questionnaire according to DSM-5 criteria(PCL-5) and Conner’ s Psychological Neurology Questionnaire. Data analyzed by mean, standard deviation, Levin's test, and regression slope homogeneity and MANCOVA to test the research hypotheses. Results: The results indicated that psychodrama could lead to a significant reduction in the rate of neuropsychological functioning problems by 0. 52, in children with significant post-traumatic stress disorder level(P <0. 001). Conclusion: Therefore, it can be concluded that psychodrama is an effective treatment method not only to reduce the psychiatric, neurological problems in children, however.