Background: In December 2019, a pandemic broke out in Wuhan, China, which attracted worldwide attention and was named covid-19. The virus has caused a great deal of fear and panic among the people of the world, and the World Health Organization (WHO) has announced the outbreak of the virus in a public health emergency. The most common symptoms include fever, fatigue, and a dry cough, but it has recently been confirmed that neurological and cognitive symptoms such as headache, cognitive impairment, and paresthesia are also present. Method: In this review, all articles published until May 4, 2020 in English on the subject of covid-19 disease and its neurological and cognitive effects were examined. This search was performed through the reputable scientific databases BioRxiv, Google scholar, Scopus, PubMed and using the keywords Coronaviruses infection, COVID-19, Nervous system and the necessary information was extracted. Conclusion: In this study, reports of viral attacks on the central nervous system and the development of viral inflammation of the brain were also highlighted, and the mediating role of the immune system in fighting infection was emphasized. Lack of sense of smell and taste in infected people and its relationship with the nervous system are other important signs of the virus and are one of the first signs of an attack on the nervous system. Acute cerebrovascular disease and the process of its formation due to hypoxia and other complications of infection were also described. Therefore, it is necessary to consider the appearance of neurological symptoms in the initial evaluations, because some patients only refer to these symptoms.