In this research, the abrasion resistance of the parts manufactured by Additive Manufacturing (AM) has been experimentally analyzed. These days, the AM is widely used in various industries and the Fused Deposition Modelling (FDM) process is one of the most popular methods of fabrication in this field. Although many researches have been done to model mechanical behavior in this field, there are limited studies in wear and its modeling. In this research, to create an exact mathematical relationship between the input variables (layer thickness, raster angle, and raster distance) and the response variable (wear rate), the experimental design using the Central Composite Design (CCD) method has been employed. Moreover, twenty systematic experiments were performed to determine the response and provide a proportional regression model. Using analysis of variance (ANOVA), a mathematical model corresponding to the actual process was obtained, and the validity of the proposed model was confirmed by statistical methods. The results have indicated that the proposed model predicts the wear rate of Acrylonitrile Butadiene Styrene (ABS) parts made by FDM method with the coefficient of determination of 97. 44%. Furthermore, the results of the experimental study and experimental analysis have shown that the raster distance parameter and the effect of its interaction with the raster angle, creates the highest wear rate, and also the second-order effect of layer thickness has the most negative effect on wear rate.